Publications by authors named "Seong D"

The current study aimed to quantify the length progression of enamel microcracks (EMCs) after debonding metal and ceramic brackets, implementing OCT as a diagnostic tool. The secondary objectives included a three-dimensional assessment of EMC width and depth and the formation of new EMCs. OCT imaging was performed on 16 extracted human premolars before bonding and after debonding.

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BACKGROUND The Smovey Vibroswing exercise device consists of a circular tube containing 4 steel balls, partly covered by a cushioning handle, to strengthen the arm and shoulder muscles. This study aimed to compare the effects of using a Smovey Vibroswing versus dumbbell exercises on muscle activity and body composition of the upper limbs in 23 women under 30 years of age. MATERIAL AND METHODS Subjects were 23 women under the age of 30 years, residing in South Korea, with no musculoskeletal diseases or shoulder surgeries in the past year.

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Recently, implantable devices for treating peripheral nerve disorders have demonstrated significant potential as neuroprosthetics for diagnostics and electrical stimulation. However, the mechanical mismatch between these devices and nerves frequently results in tissue damage and performance degradation. Although advances are made in stretchable electrodes, challenges, including complex patterning techniques and unstable performance, persist.

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An unprecedented amount of SARS-CoV-2 data has been accumulated compared with previous infectious diseases, enabling insights into its evolutionary process and more thorough analyses. This study investigates SARS-CoV-2 features as it evolved to evaluate its infectivity. We examined viral sequences and identified the polarity of amino acids in the receptor binding motif (RBM) region.

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Implantable electrochemicals stand out as promising candidates for resolving peripheral nerve injuries. However, challenges persist in designing bioelectronic materials that mimic tissue due to modulus matching, conformal adhesion, and immune responses. Herein, we present a nerve-mimicking design rationale for biocompatible hydrogel-based electroceuticals with a tissue-like modulus, robust and conformal tissue adhesion, exceptional mechanical toughness, and efficient stress dissipation.

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  • Translational biology emphasizes the connection between clinical phenotypes and biological profiles, helping to transform existing clinical data into actionable biological insights.
  • Traditional computational tools struggle with small datasets and complex clinical data, but state-of-the-art foundation models can effectively analyze electronic health records (EHR) to generate detailed proteomics profiles for pregnant patients.
  • This research identifies a proteomic signature related to gestational diabetes, highlighting the potential of using FM-derived EHR data to enhance disease understanding and improve therapeutic strategies in a more efficient and economical way.
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  • * Traditional evaluation methods are insufficient to assess the complex properties of the cornea, highlighting the need for advanced imaging techniques.
  • * This study introduces a deep learning approach for accurately analyzing bioengineered corneal grafts using optical coherence tomography, offering detailed quantitative assessments and showing promise for clinical use in human eye surgeries.*
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  • The study examined how endurance exercise training (EXT) can help mitigate health risks associated with disrupted circadian rhythms (CR) in both shift workers and experimentally affected rats.
  • Researchers found that CR disturbance leads to negative changes in skeletal muscle, including increased dyslipidemia and decreased mitochondrial functioning.
  • Results indicated that EXT can improve cholesterol levels and enhance mitochondrial biogenesis and antioxidant defenses, suggesting it may help lower cardiovascular risks associated with CR disruptions.
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  • Scientists are studying how the virus SARS-CoV-2 changes and mutates in different regions and populations.
  • They collected lots of data to predict these mutations and found that using specific information about the virus's family (clades) helped improve their prediction models.
  • They used advanced computer models and discovered important mutation spots for upcoming virus versions, including one significant change in the Omicron variant.
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COVID-19 has already claimed over 7 million lives and has infected over 775 million people globally [1]. SARS-CoV-2, the virus that causes Covid-19, spreads primarily through droplets from infected people's airways, rendering Heating, Ventilation, and Air Conditioning (HVAC) systems critical in controlling infection risk levels in the indoor environment. To understand the dynamics of exhaled droplets and aerosols and the percentage of particles that are inhaled, escaped, recirculated, or trapped on different surfaces for a variety of environmental settings, we have presented our findings from the Computational Fluid Dynamics (CFD) modeling to investigate the impact of changing HVAC parameters in this paper.

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  • Severe fever with thrombocytopenia syndrome (SFTS) has a high mortality rate, especially in immunocompromised patients, often leading to severe encephalitis symptoms before death.* -
  • The SFTS virus (SFTSV) infects critical areas of the brain like the brainstem and spinal cord, resulting in respiratory and motor nerve issues.* -
  • Activated A1-reactive astrocytes in infected mice cause neuronal cell death and neuroinflammation, suggesting a potential target for future SFTS treatments, as there are currently no effective therapies.*
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Novel hearable technology is securely and comfortably positioned within the ear canal minimizing inaccuracies caused by accessory movements during activities. Despite extensive research on hearable technologies within the outer ear, there is a lack of research in the field of vascular imaging and quantitative analysis in the outer ear , which is one of the crucial factors to select the appropriate sensor position. Therefore, in this paper, we introduced optical coherence tomography angiography (OCTA)-based qualitative and quantitative analyses to visualize the inner vasculature of the outer ear to acquire vascular maps for microvascular assessments .

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Speckle patterns are a generic feature in coherent imaging techniques like optical coherence tomography (OCT). Although speckles are granular like noise texture, which degrades the image, they carry information that can be benefited by processing and thereby furnishing crucial information of sample structures, which can serve to provide significant important structural details of samples in longitudinal pre-clinical monitoring and assessments. Since the motions of tissue molecules are indicated through speckle patterns, speckle variance OCT (SV-OCT) can be well-utilized for quantitative assessments of speckle variance (SV) in biological tissues.

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  • * The development of accurate predictive models and a deeper understanding of PTB-related problems is essential for improving outcomes.
  • * The authors explore how advancements in artificial intelligence can analyze diverse data types, including health records, biological data, and social health factors, to enhance insights into PTB.
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  • Anesthesiology significantly influences patient care and outcomes, yet there's a lack of insights into current research trends in the field.
  • A data-driven analysis using over 32,000 PubMed abstracts helped identify key topics and time-based trends within anesthesiology research from 2000 to 2022.
  • Findings revealed eight main research areas, trends in specific topics like "Cells & Proteomics" and "Pulmonology," and highlighted rising interests in "Aneurysms," "Covid 19," and "Artificial Intelligence."
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To identify the vascular alteration by photodynamic therapy (PDT), the utilization of high-resolution, high-speed, and wide-field photoacoustic microscopy (PAM) has gained enormous interest. The rapid changes in vasculature during PDT treatment and monitoring of tumor tissue activation in the orthotopic pancreatic cancer model have received limited attention in previous studies. Here, a fully two-axes waterproof galvanometer scanner-based photoacoustic microscopy (WGS-PAM) system was developed for in vivo monitoring of dynamic variations in micro blood vessels due to PDT in an orthotopic pancreatic cancer mouse model.

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  • This study aimed to evaluate surface smoothness and internal bubbles in resin used for treating non-cancerous cervical lesions (NCCLs) using optical coherence tomography (OCT).* -
  • Cross-sectional images of treated NCCLs were analyzed to examine surface quality between dental structures and quantify the amount of resin used, yielding 3D representations of the resin's inner structure.* -
  • The findings highlighted OCT's ability to measure surface quality and detect internal bubbles, making it a valuable tool for both qualitative and quantitative assessments in dental treatment of NCCLs.*
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The net CO2 assimilation (A) response to intercellular CO2 concentration (Ci) is a fundamental measurement in photosynthesis and plant physiology research. The conventional A/Ci protocols rely on steady-state measurements and take 15-40 min per measurement, limiting data resolution or biological replication. Additionally, there are several CO2 protocols employed across the literature, without clear consensus as to the optimal protocol or systematic biases in their estimations.

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The worst forest fires in Korean history broke out on March 4, 2022 and lasted for ten days. In order to monitor the catastrophic forest fires, Geostationary Korea Multi-Purpose Satellite (GK)-2 A Advanced Meteorological Imager (AMI) and GK-2B Geostationary Environment Monitoring Spectrometer (GEMS) data were used in this study. Aerosol optical depth (AOD) irretrievable for the biomass-burning aerosols produced with water vapor classified as could-contaminated, was reconstructed by ultraviolet aerosol index (UVAI).

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  • There is a growing need for soft materials that can securely adhere to nerve tissues without the need for sutures, as this can improve surgical outcomes and recovery.
  • The development of a novel material called sticky and strain-gradient artificial epineurium (SSGAE) addresses this challenge by providing strong adhesion to wet nerves and anti-inflammatory properties.
  • The SSGAE, designed with a structure that mimics natural skin, has shown success in stabilizing nerve repairs in both rodent and nonhuman primate models, showcasing its potential for real-world medical applications in peripheral nerve repair.
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The bluetongue virus (BTV) is a significant animal pathogen with economic implications in the ruminant industry. Despite global reports on BTV detection and epidemiologic investigations, limited studies have focused on the virus in the ROK. In this study, BTV epidemiological research was conducted on blood samples from cattle and goat farms across nine regions during 2013-2014.

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Characterizing plant material is crucial in terms of early disease detection, pest control, physiological assessments, and growth monitoring, which are essential parameters to increase production in agriculture and prevent unnecessary economic losses. The conventional methods employed to assess the aforementioned parameters have several limitations, such as invasive inspection, complexity, high time consumption, and costly features. In recent years, optical coherence tomography (OCT), which is an ultra-high resolution, non-invasive, and real-time unique image-based approach has been widely utilized as a significant and potential tool for assessing plant materials in numerous aspects.

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To construct tissue-like prosthetic materials, soft electroactive hydrogels are the best candidate owing to their physiological mechanical modulus, low electrical resistance and bidirectional stimulating and recording capability of electrophysiological signals from biological tissues. Nevertheless, until now, bioelectronic devices for such prostheses have been patch type, which cannot be applied onto rough, narrow or deep tissue surfaces. Here we present an injectable tissue prosthesis with instantaneous bidirectional electrical conduction in the neuromuscular system.

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Sebum is an important component of the skin that has attracted attention in many fields, including dermatology and cosmetics. Pore expansion due to sebum on the skin can lead to various problems. Therefore, it is necessary to analyze the morphological characteristics of sebum.

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Polymers for implantable devices are desirable for biomedical engineering applications. This study introduces a water-resistant, self-healing fluoroelastomer (SHFE) as an encapsulation material for antennas. The SHFE exhibits a tissue-like modulus (approximately 0.

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