Publications by authors named "Seok Joo Moon"
Purpose: Numerous patients experience long-term complications after hematopoietic stem cell transplantation (HSCT). This study aimed to identify the frequency and risk factors for psychiatric and endocrine complications following HSCT through big data analyses.
Materials And Methods: We established a cohort of patients with hematologic disease who underwent HSCT in Korea between 2010 and 2012 using the Health Insurance Review & Assessment Service data.
Background: Bone-modifying agents (BMA) are key components in the management of cancer patients with bone metastasis. Despite their clinical benefits, the use of BMA is associated with dental adverse events (AEs) including medication-related osteonecrosis of the jaw (MRONJ). This study investigated the frequency of dental surveillance before BMA treatment and the prevalence of dental AEs including MRONJ, after BMA treatment in patients with bone metastasis from breast and prostate cancer using data from the national health insurance system.
View Article and Find Full Text PDFBackground/aims: The prognosis of patients with idiopathic pulmonary fibrosis (IPF) and respiratory failure requiring mechanical ventilation is poor. Therefore, mechanical ventilation is not recommended. Recently, outcomes of mechanical ventilation, including those for patients with IPF, have improved.
View Article and Find Full Text PDFBackground: Diabetes is associated with an increased risk of Parkinson's disease dementia (PDD); however, it is unknown whether this association is dependent on continuous hyperglycemia, hypoglycemic events, or glycemic variability. We aimed to investigate the relationship between visit-to-visit fasting glucose variability and PDD development in patients with Parkinson's disease (PD).
Methods: Using data from the Korean National Health Insurance Service, we examined 9,264 patients aged ≥40 years with Parkinson's disease (PD) who underwent ≥3 health examinations and were followed up until December 2019.
Background: This study aimed to evaluate the annual trends of transfusion rates and utilization of blood management agents in total knee arthroplasty (TKA) based on the operation type and to analyze the risk factors of transfusion after TKA.
Methods: Using the Korean National Insurance claims database of 797,106 primary and revision TKAs between January 2008 and October 2019, data on the patients' characteristics, comorbidities, utilization of transfusion, and blood management agents were collected. The patients were categorized into three groups based on the operation type: primary, revision, and simultaneous bilateral TKA.
Purpose: BRCA1/2 mutations are well-known risk factors for breast and ovarian cancers in women. Risk-reducing salpingo-oophorectomy (RRSO) is the standard treatment for preventing ovarian cancer with BRCA mutations. Postmenopausal syndrome (symptoms after RRSO can be alleviated by hormone replacement therapy (HRT); however, the use of HRT in carriers of BRCA mutations has been controversial because of the concern that HRT increases the risk of breast cancer.
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- A large cohort study involving over 594,000 participants aimed to explore the relationship between statin use and the development of various types of tendinopathy disorders, such as trigger finger and rotator cuff tendinopathy.
- Results indicated that statin users had a significantly higher risk of developing tendinopathy compared to nonusers, with a hazard ratio of 1.435.
- Interestingly, the study found that the risk of tendinopathy decreased with higher cumulative doses of statins, suggesting that the more statins were taken, the lower the risk of developing these disorders.
Background: Poor dental health is correlated with an increased risk of cancer. Using a nationwide population cohort database, we investigated which cancer is highly associated with poor dental health and which dental indicator mostly influences cancer risk.
Methods: This study was conducted using the National Health Checkups (NHC) and National Health Insurance System (NHIS) database in Korea.
Introduction: We aimed to investigate the incidence of Parkinson's disease (PD) by age and year for each sex as well as the modifiable risk factors for PD. Using data from the Korean National Health Insurance Service, 938,635 PD and dementia-free participants aged ≥40 years who underwent general health examinations were followed to December 2019.
Methods: We analyzed the PD incidence rates according to age, year and sex.
Article Synopsis
- A study compared factors influencing direct admissions to regional cardiocerebrovascular centers for patients with acute ischemic stroke (AIS) and acute myocardial infarction (AMI), revealing notable differences.
- Among the 26,824 patients analyzed, 66.6% with AIS and 48.2% with AMI were directly admitted, with variations in influencing factors such as previous health conditions and education level.
- Emergency medical service (EMS) usage emerged as the most significant factor for both conditions, indicating the need for better public education on symptoms and EMS utilization for timely hospital admissions.
Background: We analyzed the effect of statins in patients with hormone receptor-positive (HR+) metastatic breast cancer treated with everolimus + exemestane (EverX).
Materials And Methods: We conducted a nationwide retrospective cohort study using the National Health Insurance database with patients who received EverX for metastatic breast cancer between 2011 and 2019.
Results: Of 224,948 patients diagnosed with breast cancer, 1749 patients who received EverX for at least 30 days were included.