Publications by authors named "Seo Young Jo"

Polyhydroxyalkanoates (PHAs) are natural biopolyesters produced by microorganisms that represent one of the most promising candidates for the replacement of conventional plastics due to their complete biodegradability and advantageous material properties which can be modulated by varying their monomer composition. Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) [P(3HB-co-3HV)] has received particular research attention because it can be synthesized based on the same microbial platform developed for poly(3-hydroxybutyrate) [P(3HB)] without much modification, with as high productivity as P(3HB). It also offers more useful mechanical and thermal properties than P(3HB), which broaden its application as a biocompatible and biodegradable polyester.

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Convective extreme El Niño (CEE) events, characterized by strong convective events in the eastern Pacific, are known to have a direct link to anomalous climate conditions worldwide, and it has been reported that CEE will occur more frequently under greenhouse warming. Here, using a set of CO ramp-up and ramp-down ensemble experiments, we show that frequency and maximum intensity of CEE events increase further in the ramp-down period from the ramp-up period. These changes in CEE are associated with the southward shift of the intertropical convergence zone and intensified nonlinear rainfall response to sea surface temperature change in the ramp-down period.

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Article Synopsis
  • Bio-based manufacturing of platform chemicals and polymers is gaining traction in biorefineries, aimed at sustainable and carbon-neutral industries.
  • Key products like bio-based diamines, aminocarboxylic acids, and diacids serve as monomers for versatile polyamides and are also precursors for valuable chemicals.
  • Recent advancements in their production have been made through metabolic engineering of microbial consortia and optimizations in bioconversion processes, enhancing efficiency and sustainability.
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Since the 20th century, plastics that are widely being used in general life and industries are causing enormous plastic waste problems since improperly discarded plastics barely degrade and decompose. Thus, the demand for polyhydroxyalkanoates (PHAs), biodegradable polymers with material properties similar to conventional petroleum-based plastics, has been increased so far. The microbial production of PHAs is an environment-friendly solution for the current plastic crisis, however, the carbon sources for the microbial PHA production is a crucial factor to be considered in terms of carbon-neutrality.

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Cupriavidus necator, a versatile microorganism found in both soil and water, can have both heterotrophic and lithoautotrophic metabolisms depending on environmental conditions. C. necator has been extensively examined for producing Polyhydroxyalkanoates (PHAs), the promising polyester alternatives to petroleum-based synthetic polymers because it has a superior ability for accumulating a considerable amount of PHAs from renewable resources.

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Article Synopsis
  • The global reliance on petroleum has resulted in significant environmental issues like climate change, prompting a shift towards biorefineries that use microorganisms for sustainable production.
  • C4 alcohols, important chemicals for biofuels and other products, can be effectively produced through DCEO biotechnology and metabolic engineering techniques.
  • The review highlights production strategies, synthetic tools, and the development of microbial cell factories to optimize processes for cost-effective industrial production of C4 alcohols.
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Advances in scientific technology in the early twentieth century have facilitated the development of synthetic plastics that are lightweight, rigid, and can be easily molded into a desirable shape without changing their material properties. Thus, plastics become ubiquitous and indispensable materials that are used in various manufacturing sectors, including clothing, automotive, medical, and electronic industries. However, strong physical durability and chemical stability of synthetic plastics, most of which are produced from fossil fuels, hinder their complete degradation when they are improperly discarded after use.

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Sucrose utilization has been established in Escherichia coli strains by expression of Mannheimia succiniciproducens β-fructofuranosidase (SacC), which hydrolyzes sucrose into glucose and fructose. Recombinant E. coli strains that can utilize sucrose were examined for their abilities to produce poly(3-hydroxybutyrate) [P(3HB)] and poly(3-hydroxybutyrate-co-lactate) [P(3HB-co-LA)] from sucrose.

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Article Synopsis
  • Concerns about pollution from non-degradable plastics have led to increased interest in biodegradable plastics, particularly polyhydroxyalkanoates (PHAs), which are produced by microorganisms and possess similar properties to conventional plastics.
  • * Research efforts are focused on understanding how PHAs are synthesized and improving microbial strains to produce them efficiently for industrial use, leveraging advancements in biotechnology.
  • * This review highlights recent developments in microbial production of PHAs and other non-natural polyesters, aiming to pave the way for engineering microorganisms as sustainable alternatives in plastic manufacturing.
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