Publications by authors named "Seo Won Song"
Article Synopsis
- Recent studies suggest that Mesenchymal Stem Cells (MSCs) could be a promising treatment for Alopecia Areata (AA) due to their ability to suppress the immune response.
- In animal experiments, MSC therapy showed improved hair regrowth and reduced local inflammatory cytokines in mice with AA compared to a control group.
- The treatment also normalized important signaling pathway genes and growth factors involved in hair cycle regulation, indicating the need for further research on MSCs' effectiveness for AA treatment.
Article Synopsis
- Cyclosporine (CS) is commonly used to treat moderate to severe atopic dermatitis (AD), but its long-term effects on blood pressure are not well understood.!
- A study analyzed data from over 1.8 million AD patients to examine how CS dosage affects the risk of hypertension, finding that current CS use significantly increases this risk.!
- While low-dose CS has a low incidence of hypertension, higher dosages and longer usage are linked to a greater likelihood of developing high blood pressure, suggesting caution is needed for long-term prescriptions.!
Several studies have reported the pathogenic role of in atopic dermatitis (AD); the significance of 's influence on AD needs to be further investigated. Dupilumab, a monoclonal antibody to anti-Interleukin (IL) 4Rα, and ruxolitinib, a Janus kinase (JAK)1/2 inhibitor, are the first approved biologics and inhibitors widely used for AD treatment. In this study, we aimed to investigate how () affects the skin barrier and inflammation in AD and interacts with the AD therapeutic agents ruxolitinib and anti-IL4Rα.
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