Publications by authors named "Senyu Wang"

Marine microalgae are a rich source of natural products, and their amino acid-based antimicrobial agents are usually obtained by enzymatic hydrolysis, which is inefficient and limits the research on antimicrobial peptides (AMPs) from microalgae. In this study, is used as a model to predict antimicrobial peptides through high-throughput methods, and 471 putative peptides are identified based on the de novo transcriptome technique. Among them, three short peptides, P1, P6, and P7 were found to have antimicrobial activity against , , , and yeast , and they showed no hemolytic activity even at higher concentrations up to 10 mg/mL.

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Background: Ferroptosis can be used as a powerful predictor of cancer prognosis. HPV persistent infection is the main cause of cervical cancer, so it is very important to improve the prognosis of patients. Therefore, it is necessary to explore the value of HPV-ferroptosis related genes as prognostic biomarkers of cervical cancer patients.

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Various yellowish-green persistent phosphors of YLuGdAlGaO:0.05Ce ( = 0-1, = 0-1, = 1-4) were successfully synthesized by the one-step high-temperature solid-state reaction method in air. The effects of simultaneous doping of Lu, Gd and Ga on the luminescence properties of the phosphors were investigated in detail for the first time.

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Guanylate binding protein 1 (GBP1) is the most concerned member of the GBP family, which has a series of effects such as anti-infection and anti-angiogenesis. Its role in malignant tumors including cervical cancer is still controversial. We aim to explore the effects of GBP1 on cervical cancer through bioinformatics and related experiments.

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Lung cancer has the highest mortality rate of all cancers, and LUAD's survival rate is particularly poor. Erythropoietin receptor (EPOR) can be detected in lung adenocarcinoma (LUAD), however, the expression levels and prognostic value of EPOR in LUAD are still unclear. In our study, clinicopathological data of 92 LUAD patients between January 2008 and June 2016, multiple bioinformatics databases and immunohistochemistry were used to explore the EPOR expression, the mutant genes affecting EPOR expression, and the correlation of EPOR expression with oxidative stress - related genes, prognosis, immune microenvironment.

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We demonstrated an ultra-broadband supercontinuum (SC) laser source with a wavelength range spanning the near-infrared (NIR) to mid-infrared (MIR) region. The SC spectrum was generated in a very short piece of highly nonlinear silica fiber (HNLF) which has a zero-dispersion wavelength (ZDW) of 1.55 µm.

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This article proposes and numerically demonstrates a widely tunable on-chip Raman soliton source based on a cascaded AsSe waveguide. The cascaded sub-waveguides (input and output) with varying widths act as nonlinear devices, while a tapered waveguide is arranged between them to achieve low-loss transmission. The input waveguide provides anomalous dispersion in the near-infrared band, thereby enabling the 1.

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Ferroptosis has been identified as a potent predictor of cancer prognosis. Currently, cervical cancer ranks among the most prevalent malignant tumors in women. Enhancing the prognosis for patients experiencing metastasis or recurrence is of critical importance.

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Article Synopsis
  • Phosphoenolpyruvate carboxykinase (PEPCK) is crucial for gluconeogenesis, and this study explores its evolutionary differences, particularly in Mollusca with two distinct lineages: Mollusca_PEPCK-1 and Mollusca_PEPCK-2.
  • CgPEPCK-1 and CgPEPCK-2 from the Pacific oyster Crassostrea gigas shared structural similarities but showed different expression levels and functions; CgPEPCK-2 had higher activity, while CgPEPCK-1 was linked to immune responses against infections.
  • The findings suggest that the PEPCK gene family has evolved in Mollusks to specialize, with CgPE
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Background: Erythropoietin receptor (EPOR), a member of the cytokine class I receptor family, mediates erythropoietin (EPO)-induced erythroblast proliferation and differentiation, but its significance goes beyond that. The expression and prognosis of in cancer remain unclear.

Methods: This study intended to perform a pan-cancer analysis of by bioinformatics methods.

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In this paper, a novel chain-shaped long-period fiber grating (CS-LPFG) for strain measurement is investigated and experimentally demonstrated. This structure is achieved by polishing periodic slant planes on a single-mode fiber with a high-frequency laser. The chain-shaped structures improved the strain sensitivity of the sensor while shortening the length of the sensing unit.

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In this Letter, a novel, to the best of our knowledge, parallel inclined planes long period fiber grating (PIP-LPFG) for strain measurement is proposed. This structure is fabricated by a high frequency laser, which has polished periodic parallel inclined planes on a single mode fiber (SMF). Refractive index modulation (RIM) over a large area on the surface of the SMF significantly shortens the total length of the grating, and the structure of parallel inclined planes efficiently enhance the strain sensitivity of PIP-LPFG.

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Article Synopsis
  • * Researchers analyzed frozen cancer specimens and found a significantly high rate of multiple HPV infections (92.5%) compared to commercial testing methods, revealing over 13,000 integration events across many human genes.
  • * The results indicated specific “hotspots” in the human genome where HPV integration predominates, affecting gene expressions, including PD-L1, a protein involved in immune response regulation in cancer cells.
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Aims: The aim of this study was to explore the correlation between red blood cell distribution width (RDW) and Preganecy Heypertion Disease (PHD) .

Methods: A retrospective study was carried out involving 149 pregnancies with PHD(67 gestational hypertension, 39 Mild preeclampsia, 24 severe preeclampsia and 19 eclampsia) and 70 health pregnant women as controls. The data of RDW were reviewed from antenatal and delivery records.

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