Electrophysiologic characteristics and clinical correlation of right ventricular activation during left bundle branch area pacing (RV-LBBAP study).

Background: Left bundle branch area pacing (LBBAP) results in a right bundle branch (RBB) delay pattern because of preexcitation of the left bundle. The mechanism of right ventricular (RV) activation during LBBAP is largely unknown.

Objective: The aim of the study was to analyze the electrophysiologic characteristics of RV activation by mapping the RBB during LBBAP and its clinical correlation.

A Rapid and Simplified Approach to Correct Atmospheric Absorptions in Infrared Spectra.

Infrared (IR) spectroscopy is a powerful analytical technique used to identify and quantify different components within a sample. However, spectral interference from fluctuating concentrations of water vapor and CO in the measurement chamber can significantly impede the extraction of quantitative information. These temporal fluctuations cause absorption variations that interfere with the sample's spectrum, making accurate analysis challenging.

New-Onset Left Ventricular Dysfunction After Left Bundle Branch Pacing.

Background: Left bundle branch pacing (LBBP) provides stable pacing parameters and has been suggested as an alternative for right ventricular pacing and cardiac resynchronization therapy.

Objectives: The aim of the study was to assess the incidence and etiology of new-onset left ventricular dysfunction (NOLVD) following LBBP in patients with baseline normal left ventricular (LV) function and cardiomyopathy patients with normalized LV function.

Methods: Patients undergoing successful LBBP for symptomatic bradyarrhythmia or as an alternative to cardiac resynchronization therapy were included.

Retrograde Conduction in Left Bundle Branch Block: Insights From Left Bundle Branch Pacing.

Background: Biventricular pacing is a well-established therapy for patients with heart failure (HF), left bundle branch block (LBBB) and left ventricular (LV) dysfunction. Left bundle branch pacing (LBBP) has emerged as an alternative to biventricular pacing.

Objectives: The aim of this study was to assess the retrograde conduction properties of the left bundle branch in patients with nonischemic cardiomyopathy and LBBB during LBBP and its clinical implications.

Particles in Exhaled Air (PExA): Clinical Uses and Future Implications.

Access to distal airway samples to assess respiratory diseases is not straightforward and requires invasive procedures such as bronchoscopy and bronchoalveolar lavage. The particles in exhaled air (PExA) device provides a non-invasive means of assessing small airways; it captures distal airway particles (PEx) sized around 0.5-7 μm and contains particles of respiratory tract lining fluid (RTLF) that originate during airway closure and opening.

Towards quantifying biomarkers for respiratory distress in preterm infants: Machine learning on mid infrared spectroscopy of lipid mixtures.

Neonatal respiratory distress syndrome (nRDS) is a challenging condition to diagnose which can lead to delays in receiving appropriate treatment. Mid infrared (IR) spectroscopy is capable of measuring the concentrations of two diagnostic nRDS biomarkers, lecithin (L) and sphingomyelin (S) with the potential for point of care (POC) diagnosis and monitoring. The effects of varying other lipid species present in lung surfactant on the mid IR spectra used to train machine learning models are explored.

Exploratory Study on Micronuclei and Metanuclear Abnormalities in Exfoliated Buccal Cells of COVID-19 Suspected Patients.

Context: SARS-CoV-2 virus causes COVID-19 by infecting nasal and oral cavities primarily by attaching its spike proteins to ACE 2 receptors expressed in epithelial cells.

Aim: This study was done to evaluate the micronucleated cell count, metanuclear abnormalities, and genotoxic factor in exfoliated buccal mucosal cell among the COVID-19 suspected patients.

Settings And Design: This cross-sectional study was conducted at AIIMS, Mangalagiri, between August and October 2022.

Effectiveness of promethazine on preoperative and intraoperative sequelae in cleft palate surgeries.

Introduction: Anxiety and nosocomial infection are the most common reported problems in children undergoing cleft surgeries. Research shows that there is an enigma in the use of antihistamine therapy in children for the management of upper respiratory tract infection. 'Promethazine' is a first-generation H1 receptor antagonist, and antihistamine also has strong sedative effects.

Is left bundle branch pacing (LBBP) associated with better depolarization and repolarization kinetics than right ventricular mid septal pacing (RVSP)? - Comparison of frontal QRS -T angle in patients with LBBP, RVSP and normal ventricular conduction.

Aims: To assess the frontal QRS- T angle (f QRS- T angle) in patients with left bundle branch pacing (LBBP) as compared to right ventricular mid septal pacing (RVSP) implanted for symptomatic high degree atrioventricular (AV) block and to compare with control subjects with normal ventricular conduction (CSNVC) METHODS: A total of one-fifty subjects were chosen (50 patients with LBBP, 50 patients with RVSP and 50 CSNVC). The indication for pacemaker implantation was symptomatic high degree AV block. Baseline clinical and electrocardiogram (ECG) parameters like QRS duration (QRSD), QRS axis and f QRS-T angle and Ejection Fraction (EF) were assessed.

Left bundle branch pacing lead for sensing ventricular arrhythmias in implantable cardioverter-defibrillator: A pilot study (LBBP-ICD study).

Background: Left bundle branch pacing (LBBP) has been suggested as an alternative modality for biventricular pacing in cardiac resynchronization therapy (CRT)-eligible patients. As it provides stable R-wave sensing, LBBP has been recently used to provide sensing of ventricular arrhythmia in patients receiving implantable cardioverter-defibrillator (ICD) with CRT.

Objective: The aim of this study was to analyze the long-term safety and efficacy of the LBBP lead for appropriate detection of ventricular arrhythmia and delivery of antitachycardia pacing (ATP) in patients requiring defibrillator therapy with CRT.

Observations of interventricular septal behavior during left bundle branch pacing.

Introduction: Left bundle branch pacing (LBBP) involves the deployment of the lead deep inside the septum. Penetration of the septum by the lead depends on the texture of the septum, rapidity of rotations, operator experience, and implantation tools.

Objectives: The aim of our study was to assess the behavior of the lumenless lead during rapid rotations and the physiological property of the interventricular septum(IVS) during LBBP.

Outcome of Mandibular Reconstruction with Fibula free Flaps: Retrospective Analysis of Complications.

Unlabelled: Rationale: Fibula free flap has become the workhorse for head and neck reconstruction. In this retrospective study we aimed at determining the outcomes of mandibular reconstruction with fibula free flaps. Methods: Any patient who underwent a mandibulectomy and reconstructed with vascularised fibula flap was included in the study.

MAgnetic resonance imaging based DUal lead cardiac Resynchronization therapy: A prospectIve Left Bundle Branch Pacing study (MADURAI LBBP study).

Background: Cardiac resynchronization therapy (CRT) is a class I indication for left ventricular ejection fraction (LVEF) ≤35% and heart failure (HF). Left bundle branch block (LBBB)-associated nonischemic cardiomyopathy (LB-NICM) with minimal or no scar by cardiac magnetic resonance (CMR) imaging may be associated with excellent prognosis following CRT. Left bundle branch pacing (LBBP) can achieve excellent resynchronization in LBBB patients.

Identification of Novel Cytochrome C1 (CYC1) Gene Expression in Oral Squamous Cell Carcinoma- An Evaluative Study.

Introduction: Cytochrome C1 (CYC1) is an important subunit of mitochondrial complex III and plays a vital role in oxidative phosphorylation (OXPHOS) and reactive oxygen species generation. Overexpression of the CYC1 gene has been implicated in cancer development and its prognosis previously, but unexplored in head-and-neck squamous cell carcinomas (HNSCC), especially oral squamous cell carcinoma (OSCC).

Materials And Methods: CYC1 m-RNA expression and gene alterations were assessed using the Cancer Genome Atlas dataset in HNSCC and validated in OSCC tissues using real-time polymerase chain reaction (RT-PCR).

Left bundle branch pacing-optimized implantable cardioverter-defibrillator (LOT-ICD) for cardiac resynchronization therapy: A pilot study.

Left bundle branch pacing (LBBP) involves direct capture of left bundle fibers by placing the lead deep inside the interventricular septum. Several studies have shown the feasibility and efficacy of LBBP as an alternative modality for cardiac resynchronization therapy (CRT). This paper describes approach for providing cost effective CRT with defibrillator (CRT-D) by LBBP and dual chamber implantable cardioverter defibrillator (ICD) which we label as LBBP optimized ICD (LOT-ICD).

Movie Recommender Systems: Concepts, Methods, Challenges, and Future Directions.

Movie recommender systems are meant to give suggestions to the users based on the features they love the most. A highly performing movie recommendation will suggest movies that match the similarities with the highest degree of performance. This study conducts a systematic literature review on movie recommender systems.

Prevalence of oral submucous fibrosis among areca nut chewers: A systematic review and meta-analysis.

Background: Worldwide millions peoples consume AN who are at risk of OSMF. Prevalence of OSMF is reported between 0.03% and 30% irrespective of AN habit.

End-to-Side Versus End-to-End Venous Anastomosis Using Couplers in Mandibular Reconstruction: A Comparative Study.

Purpose: This study compares the advantages of end-to-side technique over end-to-end technique for venous anastomosis using couplers.

Methods: Patients were divided into group I and group II based on end-to-side and end-to-end techniques, respectively. Intraoperative anastomotic time, flap ischemic time, and postoperatively flap vitality were the parameters evaluated.

Abutment conditions in faulty prosthesis among Indians.

A faulty prosthesis can cause damage more than relief. Poor people who cannot afford specialty treatment prefer to go to unregistered dental practitioners who are less expensive. Therefore, it is of interest to record the presence and type of old faulty prosthesis and its effect on surrounding structures.

Association of occlusal wear facets in patients with temporomandibular disorders.

Occlusal changes were important factors in temporomandibular disorder (TMD). It is of interest to evaluate the association of occlusal wear facets in TMD patients. We used a dataset of 49 patients with and without TMD for this study.