Publications by authors named "Senouci Karima"

Article Synopsis
  • Pyoderma vegetans (PV) is a rare skin condition characterized by neutrophilic inflammation, and its cause is not well understood.
  • There are currently no official treatment guidelines for PV, with systemic steroids typically being the initial treatment option, but they often lead to recurrences when stopped.
  • A study tested doxycycline at a dosage of 200 mg per day for four weeks, showing significant improvement in PV symptoms, suggesting it may be a useful alternative that reduces the reliance on systemic steroids.
View Article and Find Full Text PDF
Article Synopsis
  • Phytophotodermatitis refers to skin reactions that occur when certain plant substances come into contact with skin and are worsened by sunlight exposure.
  • These skin eruptions are primarily linked to compounds called furocoumarins, which include psoralens, xanthotoxins, and bergaptenes.
  • The condition involves two main mechanisms of skin sensitivity to sunlight: phototoxicity, which causes a direct reaction, and photoallergy, which is an immune response.
View Article and Find Full Text PDF
Article Synopsis
  • Deep dermatophytosis is a serious skin infection caused by fungi called Dermatophytes, which can lead to various complications, including deeper skin issues and widespread infections.
  • A case report details a 23-year-old man with scarring alopecia and subcutaneous abscesses, diagnosed with a severe form of dermatophytosis caused by Trichophyton Rubrum.
  • The patient had a mutation in the CARD9 gene, a risk factor identified in the Mediterranean, and after surgery to drain the abscesses and antifungal treatment, he recovered well.
View Article and Find Full Text PDF

Kaposi's sarcoma (KS) is a proliferative and multifocal disease with a double vascular and fibroblastic cell component, of mucocutaneous and visceral expression. It is a multifocal tumoral process, hyperplastic in nature without metastatic potential, induced by the human herpes virus 8 (HHV8). Paraneoplastic syndromes (PS) in KS are rare, with only a small number of cases reported and we have found no previous descriptions of a paraneoplastic scleroderma in KS in the literature.

View Article and Find Full Text PDF

Cutaneous tuberculosis represents the fifth extrapulmonary form in Morocco after pleural, lymph node, urogenital, and intestinal tuberculosis. It is recognized to form a continuous immunopathologic spectrum, ranging from a high intensity to a low intensity of cell-mediated immunity, which explains the multiplicity and heterogeneity of anatomo-clinical forms. Association of multiple forms in the same patient is really rare.

View Article and Find Full Text PDF

Sneddon-Wilkinson disease is a benign amicrobial pustulosis belonging to the spectrum of neutrophilic dermatoses. It is characterized by evident stereotypic clinical features, including, in most cases, pustular lesions of the trunk and prominent skin folds. This pustulosis may be associated with other diseases (IgA monoclonal gammopathy, rheumatoid arthritis, neoplasms or other neutrophilic dermatoses) and therefore requires regular follow-up.

View Article and Find Full Text PDF

A woman in her 50s presented with total scarring ulcerated alopecia evolving for 10 years, and a recent budding tumour on the lower lip. Clinical examination revealed an associated exfoliated and infiltrated erythroderma with ulcerated cutaneous tumours of the legs, palmoplantar hyperkeratosis, hepatosplenomegaly and diffuse lymphadenopathies.Dermatoscopy of the scalp, leg tumours and infiltrated skin showed a typical yellowish background overlaid by arborescent vessels and whitish areas.

View Article and Find Full Text PDF

Phaeohyphomycosis refers to uncommon infections due to a large group of heterogeneous organisms called "dematiaceous fungi". Here, we report a rare case of subcutaneous phaeohyphomycosis in an immunocompetent carpenter, presenting as multiple verrucous and confluent papulo-nodules of the right leg, and likely due to traumatic inoculation. The pathogenic fungal species was identified as , according to macroscopic and microscopic morphological characteristics of the colonies.

View Article and Find Full Text PDF

Naevus unius lateris is a rare congenital hamartoma, originating from the ectoderm. It is considered as a verruquous variant of the epidermal naevus. Given its extensive unilateral distribution, it is frequently associated with neurological, musculoskeletal, auditory and visual abnormalities.

View Article and Find Full Text PDF

Hypereosinophilic syndrome (HES) is a rare haematologic disorder characterised by unexplained, persistent eosinophilia with organ involvement. We report the case of a 74-year-old patient who presented with a pemphigoid-like bullous rash as the only manifestation of an HES. This report highlights the importance of the dermatological manifestations of this potentially life-threating condition that may initially present as a skin-limited disease.

View Article and Find Full Text PDF