Publications by authors named "Senming Xu"
JOURNAL/nrgr/04.03/01300535-202412000-00028/figure1/v/2024-04-08T165401Z/r/image-tiff Immune changes and inflammatory responses have been identified as central events in the pathological process of spinal cord injury. They can greatly affect nerve regeneration and functional recovery.
View Article and Find Full Text PDFObjectives: This review aims to assess the efficacy of transcutaneous electrical nerve stimulation (TENS) for neurogenic bladder after spinal cord injury (SCI).
Materials And Methods: A systematic search was conducted of seven electronic data bases from inception to Dec 31, 2022, to identify randomized controlled trials that studied TENS for neurogenic bladder after SCI. The primary outcomes were maximum cystometric capacity (MCC) and residual urine volume (RUV).
Article Synopsis
- Ischemic stroke (IS) is a major neurological issue linked to long-term disabilities, and the study focuses on how inflammation and ferroptosis contribute to its development through a competing endogenous RNA (ceRNA) network.
- The research identified 178 differentially expressed messenger RNAs tied to IS, revealing a significant correlation with inflammatory pathways and ferroptosis mechanisms, alongside notable immune cell differences in stroke patients.
- Key biomarkers, including three specific miRNAs, one mRNA (TLR4), and one lncRNA (NEAT1), were highlighted as potential targets for IS therapy, suggesting that the ceRNA network plays a crucial role in the inflammation and ferroptosis related to the disease.
Background: In recent years, non-invasive brain stimulation (NIBS) has been used for motor function recovery. However, the effects of NIBS in populations with spinal cord injury (SCI) remain unclear. This study aims to conduct a meta-analysis of the existing evidence on the effects and safety of NIBS against sham groups for motor dysfunction after SCI to provide a reference for clinical decision-making.
View Article and Find Full Text PDFBackground: In recent years, with the further research of human genome scanning, the relationship between matrix metalloproteinase-9 (MMP-9) gene polymorphisms and many diseases has aroused increased attention. But there is little research on the relationship between MMP-9 gene polymorphisms and ischemic stroke (IS). This study was conducted to evaluate the relationships between the rs3918242 and rs17577 polymorphisms in the MMP-9 gene and IS in a Chinese population.
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