Publications by authors named "Sener Yalcin"
Detecting rare cells within blood has numerous applications in disease diagnostics. Existing rare cell detection techniques are typically hindered by their high cost and low throughput. Here, we present a computational cytometer based on magnetically modulated lensless speckle imaging, which introduces oscillatory motion to the magnetic-bead-conjugated rare cells of interest through a periodic magnetic force and uses lensless time-resolved holographic speckle imaging to rapidly detect the target cells in three dimensions (3D).
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- Parasitic infections are a significant global health challenge, and current screening methods are often insufficient for early diagnosis due to limited speed and sensitivity.
- A new motility-based, label-free imaging platform has been developed to quickly detect motile parasites in bodily fluids by analyzing their movement, allowing for the rapid screening of fluid samples in three dimensions.
- This innovative system has shown improved detection capabilities for trypanosomes and other motile parasites, significantly outperforming existing methods and offering a portable, cost-effective solution that could enhance diagnosis in areas with limited resources.