Publications by authors named "Sendilcoumare Kalimouttou"
Article Synopsis
- A new cholesteryl-cyclodextrin derivative was developed for making nanocapsules, which are tiny carriers for drugs.
- The structure of this derivative, named Chol-betaCD-Ac, was analyzed using advanced NMR technology.
- The nanocapsules successfully encapsulated vitamin A propionate, a poorly soluble drug, enabling stable and consistent size distribution, and facilitating better skin penetration.
Cryptosporidiosis, the leading cause of endemic and epidemic diarrhoeal disease worldwide is due to Cryptosporidium parvum, a spore-forming protozoan. Anticryptosporidial pharmacological and/or immunological agents were initially tested in immunodeficient models of cryptosporidiosis, and sinefungin exhibited a significant dose dependent curative and preventive activity. Shedding relapses observed after discontinuation of sinefungin therapy lead to identify the bile ducts as a protected reservoir that may sustain chronic infection.
View Article and Find Full Text PDF