Publications by authors named "Sen-Sen Chi"
Article Synopsis
- The study used a rat intestinal perfusion model to analyze how different combinations of ingredients in Simao Yongan Decoction affect the absorption of five anti-inflammatory compounds.
- Researchers identified chlorogenic acid, liquiritin, hyperoside, angoroside C, and isochlorogenic acid C as key ingredients and utilized UPLC-MSn to measure their absorption levels in various intestinal segments.
- Results indicated that the compatibility of these compounds significantly influences their absorption, with specific combinations yielding higher absorption rates for certain ingredients in the ileum and duodenum.
Diterpenoids are considered the major active compounds in in virtue of their special structures and activities. Herein, an analytical method was developed for rapid screening and identification of diterpenoids in using high-performmance liquid chromatography coupled with linear ion trap-Orbitrap mass spectrometry (HPLC-LTQ-Orbitrap) in negative ion mode. Two diterpenoid reference standards were first analyzed to obtain their characteristic ESI-MS/MS fragmentation patterns.
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