Publications by authors named "Sen-Kui Xu"
Benefit of [F] FDG PET/CT in the diagnosis and salvage treatment of recurrent nasopharyngeal carcinoma.
Eur J Nucl Med Mol Imaging
February 2023
Article Synopsis
- The study compared the effectiveness of PET/CT, MRI, and ultrasonography in detecting nasopharyngeal carcinoma recurrence and their impact on patient outcomes.
- Results showed that PET/CT was more sensitive than MRI for local recurrence and lymph node diagnosis, and it offered more accurate staging.
- Patients who received staging with both PET/CT and MRI had a significantly higher 3-year overall survival rate compared to those who were staged with MRI alone.
Introduction: In intensity modulated radiotherapy (IMRT) of nasopharyngeal carcinoma (NPC) patients, an effective immobilisation system is important to minimise set up deviation. This study evaluated the effectiveness of three immobilisation systems by assessing their set up deviations.
Methods: Patients were randomly assigned to one of the three immobilisation systems: (1) supine on head rest and base plate (HB); (2) supine with alpha cradle supporting the head and shoulder (AC); (3) supine with vacuum bag supporting the head and shoulder (VB).
An approximate correction method for the CT value-electron density curve of CBCT was established, through comparison and fitting with FBCT images, and applied to evaluate the therapeutic dose of IMRT. The precision of using CBCT for plan calculation was validated by comparing the dose distribution between CBCT- and FBCT-based IMRT plans. Also setup deviations were simulated to evaluate the ability of the CBCT-based calculation for detecting the dose errors caused by positioning deviation.
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