Ru Metalloligands Participate in the Construction of POM@MOF for Enhancing the Visible Photoinduced Baeyer-Villiger Oxidation Reaction.

Directed synthesis of high-efficiency visible photoinduced Baeyer-Villiger oxidation catalysts is of primary significance. Here, the isopolymolybdate anion [β-MoO] is for the first time encapsulated with the photosensitive metalloligand [Ru(bpy)(Hdcbpy)] (bpy = 2,2'-bipyridine; Hdcbpy = 2,2'-bipyridine-5,5'-dicarboxylic acid) to synthesize polyoxometalate@metal-organic frameworks, {(CdDMF)[Ru(bpy)(dcbpy)]([β-MoO])}·5DMF (Ru-Mo). The composite photocatalyst Ru-Mo not only has a light absorption of 700 nm but also shortens the photogenerated electron transfer distances and accelerates charge and proton transfer.

Subtype-specific transcription factors affect polyamine metabolism and the tumor microenvironment in breast cancer.

Background: Polyamines play important roles in cell growth and proliferation. Polyamine metabolism genes are dysregulated in various tumors. Some polyamine metabolism genes are regulated by transcription factors.

General and Fast Gas-Solid Synthesis of Functional MXenes and Derivatives on the Scale of Tens of Grams.

The rising of MXenes not only enriches the two-dimensional material family but also brings more opportunities for diverse functional applications. However, the controllable synthesis of MXenes is still unsatisfied via the common liquid-solid etching route, considering the unsolved problems like safety risk, time cost and easy oxidation. Herein, a facile yet efficient gas-solid (G-S) reaction methodology is devised by using hydrogen fluoride gas derived from fluorinated organics as the MAX etchant toward high-efficiency fabrication of multiple MXenes and their derivatives.

Heavy metals in the continuous river-estuary-sea system of the Yellow River Delta, China: Spatial patterns, potential sources, and influencing factors.

Present study investigated heavy metal pollution in the continuous upper river-estuary-sea systems of the Yellow River Delta (YRD). Significant seasonal differences (p < 0.05) for the heavy metal overall profile were observed, although there were no significant spatial variations among the different water bodies.

[Effectiveness of modified temporomandibular joint disc reduction and suture with tragus incision assisted by arthroscopy].

Objective: To investigate the effectiveness of modified temporomandibular joint disc reduction and suture with tragus incision assisted by arthroscopy for temporomandibular joint anterior disc displacement (ADD).

Methods: A clinical data of 30 patients (45 sides) with temporomandibular joint ADD, who met selective criteria and were admitted between September 2022 and February 2024, was retrospectively analyzed. Among them, 15 patients (23 sides) were treated with temporomandibular joint disc reduction and suture via small incision (open operation group), and 15 patients (22 sides) with modified temporomandibular joint disc reduction and suture with tragus incision assisted by arthroscopy (arthroscopy group).

Exploration of the shared gene signatures and comorbidity mechanisms of primary aldosteronism and atrial fibrillation.

Background: Primary aldosteronism (PA) is a prevalent cause of endocrine hypertension characterized by an excess of aldosterone that can induce proinflammatory, prooxidant and profibrotic effects on the heart. Emerging evidence indicates a heightened incidence of atrial fibrillation (AF) in patients with PA, suggesting a significant association between the two conditions. However, the underlying mechanisms remain unclear.

Self-Assembled 8-Ti-Containing Polyoxomolybdate for the Photocatalytic Hydrogen Evolution.

An S-shaped 8-Ti-containing polyoxomolybdate (NH)CsNaH[Ti(GeMoO)(GeMoO)]·44HO () has been prepared under the one-pot hydrothermal method and further characterized. According to single-crystal X-ray, compound consists of two {GeMoO} and two {GeMoO} segments, which are linked with a {TiO} cluster. Moreover, the {GeMoO} fragment is rare and the first discovery, which enriches the lacunary Keggin-type family and offers the possibility of obtaining new structures.

Needle knife assisted removal of the displaced metal stent.

The removal of a metal stent with proximal displacement was challenging. We present a case where a needle knife was used to incise the duodenal papilla to remove the displaced metal stent.

Gender, BMI, and Age-Related Variations in Lower Limb Alignment Parameters and CPAK Phenotypes in Chinese Patients with Knee Osteoarthritis.

Objectives: Research on the distribution of and the variation in coronal plane alignment of the knee (CPAK) in the Chinese osteoarthritis population is limited. We aimed to establish the CPAK classification based on the characteristics of lower limb alignment in the Chinese osteoarthritis population. We also investigated variations in lower limb alignment parameters and CPAK phenotypes based on gender, body mass index (BMI), and age.

Association between grip strength, walking pace and incident peripheral artery disease: A prospective study of 430,886 UK biobank participants.

Background And Aims: Patients with peripheral artery disease (PAD) presented overall muscle weakness and reduced physical performance. Previous study focused on the impact of muscle weakness on outcomes of established PAD, however the relationship between compromised muscle function and incident PAD remained unclear.

Methods: A prospective study involving 430,886 participants aged 40-69 y from UK biobank was conducted.

PTBP1 Regulates DNMT3B Alternative Splicing by Interacting With RALY to Enhance the Radioresistance of Prostate Cancer.

Radiotherapy is a curative arsenal for prostate cancer (PCa), but radioresistance seriously compromises its effectiveness. Dysregulated RNA splicing factors are extensively involved in tumor progression. Nonetheless, the role of splicing factors in radioresistance remains largely unexplored in PCa.

TRPA1 protects against contrast-induced renal tubular injury by preserving mitochondrial dynamics via the AMPK/DRP1 pathway.

Mitochondrial dysfunction and oxidative stress are involved in the development of contrast-induced acute kidney injury (CI-AKI). The present study aimed to reveal the role of transient receptor potential ankyrin 1 (TRPA1), an oxidative sensor, in CI-AKI. Trpa1 mice with Trpa1 conditionally knocked out in renal proximal tubular (PT) cells, Trpa1 overexpression mice (Trpa1-OE), and TRPA1 agonists and antagonists were used to study its function in a mouse model of iohexol-induced CI-AKI.

The presence of a sinus tract is associated with reinfection after two-stage revision surgery for prosthetic hip joint infection: a case-control study.

Background: Reinfection rates after two-stage revision (TSR) for prosthetic joint infection (PJI) range from 7.9 to 14%. Many factors, including sinus tracts, are associated with reinfection after this procedure.

Study on the Compatibility of Acrylic Acid-acrylamide-diethyldiallyl Ammonium Chloride Copolymer with Cement Slurry in CO Environment.

This paper investigates the structure and aggregation stability of acrylic acid-acrylamide-diethyldiallylammonium chloride (FA367), followed by an investigation into the impact of acidic CO environments on the interaction between FA367 and cement slurry. The results showed that FA367 formed stable flocculation in cement slurry filtrate, which was not affected by acid gas CO. With an FA367 concentration of 0.

Oncogenic fusion protein interacts with polypyrimidine tract binding protein 1 to facilitate bladder cancer proliferation and metastasis by regulating mRNA stability.

Chimeric RNAs, distinct from DNA gene fusions, have emerged as promising therapeutic targets with diverse functions in cancer treatment. However, the functional significance and therapeutic potential of most chimeric RNAs remain unclear. Here we identify a novel fusion transcript of solute carrier family 2-member 11 () and macrophage migration inhibitory factor ().

[Clinical application of free peroneal artery leaflet perforator flap in postoperative complex defect of oral cancer].

To investigate the clinical effect of a segmented perforator flap of free peroneal artery to repair a complex defect after oral cancer. Forty-eight patients with oral cancer admitted to the Department of Oral and Maxillofacial Surgery of the First Affiliated Hospital of Bengbu Medical College from January 2018 to January 2022, including 8 of buccal cancer, 7 of floor cancer, 14 of tongue cancer, 5 of retromolar cancet, 9 of maxillary gingival cancer and 5 of mandibular gingival cancer. After lesion resection, 24 patients in the experimental group used the partial perforator flap to repair the defect, and 24 patients in the control group used the single flap to repair the defect.

SUMO E3 ligase MUL1 inhibits lymph node metastasis of bladder cancer by mediating mitochondrial HSPA9 translocation.

Lymph node (LN) metastasis is the dominant cause of death in bladder cancer (BCa) patients, but the underlying mechanism remains largely unknown. In recent years, accumulating studies have confirmed that bidirectional mitochondria-nucleus communication is essential for sustaining multiple function of mitochondria. However, little has been studied regarding whether and how the translocation of mitochondrial proteins is involved in LN metastasis.

Discovery and Evaluation of Imidazo[2,1-][1,3,4]thiadiazole Derivatives as New Candidates for α-Synuclein PET Imaging.

α-synuclein (α-syn) pathologies are central to the development of synucleinopathies including Parkinson's disease (PD). Positron emission tomography (PET) imaging of α-syn pathologies is one strategy to facilitate the diagnosis, understanding, and treatment of synucleinopathies, but has been restricted by the lack of specific α-syn PET probes. In this work, we identified 2,6-disubstituted imidazo[2,1-][1,3,4]thiadiazole (ITA) as a new α-syn-binding scaffold.