Ehlers-Danlos/myopathy overlap syndrome caused by a large de novo deletion in COL12A1.

Autosomal dominant and recessive mutations in COL12A1 cause the Ehlers-Danlos/myopathy overlap syndrome. Here, we describe a boy with fetal hypokinesia, severe neonatal weakness, striking hyperlaxity, high arched palate, retrognathia, club feet, and pectus excavatum. His motor development was initially delayed but muscle strength improved with time while hyperlaxity remained very severe causing recurrent joint dislocations.

Comparative Evaluation of Orthostatic Hypotension in Patients with Diabetic Nephropathy.

Introduction: Orthostatic hypotension (OH) affects 5-20% of the population. Our study investigates the presence of OH in diabetic nephropathy (DNP) patients and the factors affecting OH in comparison with nondiabetic chronic kidney disease (NDCKD) patients.

Method: Patients presented to the nephrology clinic, and those who consented were included in the study.

[Investigating of Relation Between Fibromyalgia Syndrome and Intestinal Microbiota].

Fibromyalgia syndrome (FMS) is one of the most frequent forms of chronic widespread pain, with a reported prevalence of 3-10% in the adult population. Clinical presentation of the typical pain and the presence of associated somatic and psychological symptoms form the basis of the diagnosis. FMS is associated with nervous system dysfunction and neurotransmitters act as targets of a number of drugs approved for fibromyalgia.

The Effects of Coronavirus Disease 2019 Outbreak on Medical Students.

The coronavirus disease 2019 (Covid-19) pandemic has influenced the whole world, where after the first case was diagnosed in Turkey, educational activities were suspended and partial curfews were implemented. This study was conducted to assess the concerns faced by the medical students about their professional life due to the disrupted educational activities and related psychological effects. This is a cross-sectional survey study, conducted with self-administered questionnaires on Bezmialem Vakif University medical students, during the pandemic.

[The Investigation of Acanthamoeba and Other Free Living Amoeba in Swab Samples Obtained from Conjunctiva and Eye Lid].

Objective: In the study, it is aimed to determine the prevalence of Acanthamoeba and other free-living amoeba (FLA) species in the swab samples obtained from conjunctiva and lower eye lid.

Methods: For this purpose, swab samples from the 500 patients'eye lid and conjunctiva were obtained who admitted to Cumhuriyet University, Research and Application Hospital, Department of Ophthalmology with variety of reasons. Swab samples were carried out using sterile cotton swab in steril tubes.

Entry mechanisms of herpes simplex virus 1 into murine epidermis: involvement of nectin-1 and herpesvirus entry mediator as cellular receptors.

Unlabelled: Skin keratinocytes represent a primary entry site for herpes simplex virus 1 (HSV-1) in vivo. The cellular proteins nectin-1 and herpesvirus entry mediator (HVEM) act as efficient receptors for both serotypes of HSV and are sufficient for disease development mediated by HSV-2 in mice. How HSV-1 enters skin and whether both nectin-1 and HVEM are involved are not known.

Isolation and identification of free-living amoebae from tap water in Sivas, Turkey.

The present work focuses on a local survey of free-living amoebae (FLA) that cause opportunistic and nonopportunistic infections in humans. Determining the prevalence of FLA in water sources can shine a light on the need to prevent FLA related illnesses. A total of 150 samples of tap water were collected from six districts of Sivas province.

The prevalence, isolation and morphotyping of potentially pathogenic free-living amoebae from tap water and environmental water sources in Sivas.

Objective: To our knowledge, there is no study dealing with the prevalence of free-living amoebas (FLA) in water sources in Turkey, previous studies were mostly case presentations. The aim of the present study was to investigate the prevalence of FLA from tap water and natural water sources in different parts of the city.

Methods: In the study, 250 samples were collected from the city centre, districts and villages.

The cytopathic effects of Trichomonas vaginalis on fibroblast cell culture alone and with C. albicans and E. coli.

Objective: In this study, the cytopathic effects of Trichomonas vaginalis were investigated in L929 mouse fibroblast cell cultures (FCC) under different conditions: only parasite, or coexistence with Candida albicans and Escherichia coli.

Methods: The parasite was isolated from a symptomatic patient and cultured in Cysteine-Peptone-Liver infusion Maltose medium (CPLM). C.

The prevalence of Pediculus humanus capitis and the coexistence of intestinal parasites in young children in boarding schools in Sivas, Turkey.

The aim of this study was to investigate the prevalence of Pediculus humanus capitis and the coexistence of intestinal parasites in boarding primary schools in Sivas, Turkey. Seven hundred seventy-two students (350 [45.3%] girls, 422 [54.

[Isolation of Blastocystis spp. from human hosts and in vitro determination of different morphological forms].

Objective: Blastocystis is a highly common parasite that infects the gastrointestinal tract of many different organisms. Morphology and the appropriate classification of Blastocystis spp. has only recently been resolved with molecular biological studies.

The investigation of Entamoeba histolytica prevalence in some villages of Sivas by ELISA method.

Objective: Humans may be infected with three morphologically identical Entamoeba species; pathogenic E. histolytica, commensal E. moshkowskii and E.

Dermanyssus gallinae infestation: an unusual cause of scalp pruritus treated with permethrin shampoo.

Dermanyssus gallinae is a blood parasite of wild birds, but it is also a pest in the poultry industry. It occasionally bites mammals and thus rarely creates skin problems such as itching, papules, vesicles, and dermatitis. A 92-year-old man presented with severe itch on his head, particularly at night.

[Seroprevalence of babesiosis in cattle in Sivas].

The purpose of this study was the investigation of the seroprevalence of babesiosis in cattle in the Sivas region. Serum samples were collected from a total of 240 cattle in the Sivas region. Serum antibodies against Babesia bigemina and Babesia bovis for cattle were investigated by the indirect fluorescence antibody test (IFAT).

[Investigation of the relationship between oral and dental health and presence of Entamoeba gingivalis and Trichomonas tenax].

Objective: Entamoeba gingivalis and Trichomonas tenax can cause gingivitis and scale. In this study, the prevalence of E. gingivalis and T.

Enterobiosis in Sivas, Turkey from past to present, effects on primary school children and potential risk factors.

The prevalence of Enterobius vermicularis and potential risk factors was investigated in 2,230 pupils in Sivas between November 2006 and June 2008. A total of ten primary schools in different regions (4 located in City center, 4 in districts and 2 in villages) were classified as Region 1, Region 2 and Region 3, respectively and children completed a questionnaire about the potential risk factors. The overall egg positivity rate for E.

[Prevalence of cyst hydatic in slaughtered cattle between April and May 2005 in Sivas].

The present study was performed on 765 cattle obtained from three different slaughterhouses in Sivas, between April and May of 2005. Livers and lungs of those cattle were investigated for hydatid cysts. Out of 765 cattle, 273 (35.

In vitro evaluation of the amoebicidal activity of garlic (Allium sativum) extract on Acanthamoeba castellanii and its cytotoxic potential on corneal cells.

Free-living protozoa of the genus Acanthamoeba can cause one of the most severe, potentially sight-threatening infections of the eye, the so-called A. keratitis. A.

[The frequency of intestinal parasites in primary school children in urban and rural regions].

The aim of this study was to determine the prevalence of intestinal parasites in primary school children in Sivas and to consider the changes in frequency and variety of intestinal parasites in the light of previous studies carried out since 1985. Specimens were examined by direct microscopy and staining. In addition, the relationship of intestinal parasites with physical development, success and socio-economic situation was investigated using surveys.

[The incidence of intestinal parasites in the pediatric health and disease service and effect of these parasites on height, weight, anemia and eosinophile values].

The presence of intestinal parasites was investigated in a total of one hundred twenty patients who were hospitalized in the Cumhuriyet University Hospital, Pediatric Service, between 1 March and 1 April 2005. Parasites were found in 8 out of 120 (6.7%) patients.

[Can garlic (Allium sativum) extract be used as scolocidal agent?].

Garlic (Allium sativum L.) has been used in the public health in some of treatments for years. The most important chemical compounds of garlic are sulphide (alisin, ajoen and diallysulphure) compounds.

[Cystic echinococcosis: a study of consciousness and creating awareness].

Study was started in November 2005 and education practices and other activities have been realized between the dates of December 2005 and 5 January 2006. A wide group has been chosen from the students who are at the level of primary and secondary education to adults as a target mass to create awareness. Correspondences related to the subject have been done with Cumhuriyet University rector ship, Sivas governs ship, Sivas manager of education, Sivas mufti and essential otorizations got.

Clinical and histologic evaluations of experimental Acanthamoeba keratitis.

Amoebic keratitis, a sight-threatening, progressive corneal disease, is commonly caused by ubiquitous, pathogenic, free-living Acanthamoeba spp., which are widely distributed in the environment. We investigated clinical findings and histology of Acanthamoeba keratitis in a rat cornea model.

[The incidence of Demodex folliculorum in patients with chronic kidney deficiency].

The aim of this study was to evaluate the prevalence of Demodex folliculorum in immune suppressed patients. The present study was carried out on individuals being treated for chronic kidney deficiency and immune suppressed patients that were hospitalized in the Hemodialysis Units and Internal Disease Service of the Cumhuriyet University Hospital. Forty-seven patients with chronic kidney deficiency (CKD) and a control group of thirty-eight healthy and actively exercising individuals were included in this investigation.

[Observations on Acanthamoeba trophozoites in axenic cultures and their staining characteristics with different stains].

Acanthamoeba spp. are among the most prevalent protozoa found in the environment. The species of this genus are the causative agents of granulomatous amebic encephalitis (GAE), a fatal disease of the central nervous system (CNS), and amebic keratitis (AK), a painful sight-threatening disease of the eye.