Publications by authors named "Semlitsch B"

Background: Elective surgery in patients with insulin-treated type 2 diabetes mellitus (T2D) and the admission period in the hospital, comprise a distinctive and challenging situation for physicians, nurses, as well as for the patients themselves. There is a lack of widely accepted evidence-based and standardized approach of care in regard to perioperative management of patients with insulin-treated T2D.

Methods: The main purpose of this proof-of-concept study was to investigate whether a standardized insulin and meal regimen on the day of surgery leads to a better management of diabetes in terms of blood glucose (BG) levels.

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Objectives: To evaluate structure, documentation, treatment quality of a new implemented standardised insulin chart in adult medical inpatient wards at a university hospital.

Design: A before-after study (3 to 5 months after implementation) was used to compare the quality of old versus new insulin charts.

Setting: University Hospital Graz, Austria.

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Flow instabilities such as Rotating Stall and Surge limit the operating range of centrifugal compressors at low mass-flow rates. Employing compressible Large Eddy Simulations (LES), their generation mechanisms are exposed. Toward low mass-flow rate operating conditions, flow reversal over the blade tips (generated by the back pressure) causes an inflection point of the inlet flow profile.

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Objectives: Insulin charts represent a key component in the inpatient glycemic management process. The aim was to evaluate the quality of structure, documentation, and treatment of diabetic inpatient care to design a new standardized insulin chart for a large university hospital setting.

Methods: Historically grown blank insulin charts in use at 39 general wards were collected and evaluated for quality structure features.

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Article Synopsis
  • The study aimed to clarify the pharmacodynamic properties of insulin detemir (IDet) and insulin glargine (IGlar) by evaluating their duration of action over 30 hours using standardized methods.
  • Results showed that IDet has a mean duration of action of 25.9 hours after a single dose, compared to 19.8 hours for IGlar, while IDet has a shorter duration at steady-state.
  • The findings suggest that both insulins are suitable for once-daily dosing, but individual patient needs should be taken into account.
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Aims: To compare the pharmacodynamic properties of insulin detemir (detemir) and neutral protamine lispro (NPL) insulin using a euglycaemic glucose clamp.

Methods: In a double-blind, crossover study, 30 patients with C-peptide negative type 1 diabetes were randomly assigned to a single dose (0.4 U/kg) of detemir and NPL.

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Aims/hypothesis: This study was conducted to evaluate the long-term outcome of a structured outpatient diabetes teaching and treatment programme (DTTP) for intensified insulin therapy in patients with Type 1 diabetes, which aims to improve metabolic control without increasing the risk of severe hypoglycaemia.

Methods: All 123 diabetic outpatients (age 41+/-14 years; 64 women; BMI 23.5+/-3.

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Since 1989 the concept of empowerment and the promotion of self-care management have been generally proposed for Diabetes care. The bio-psycho-social concept of empowerment aims at encouraging the patient to develop self-care management for Diabetes treatment that is evidence-based and in accordance with the patient's goals and life style. It therefore promotes the patient's autonomy.

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Objective: Both rapid-acting insulin analogs, insulin aspart and lispro, attenuate prandial glucose excursion compared with human soluble insulin. This trial was performed to study the pharmacokinetic and pharmacodynamic profiles of insulin aspart and insulin lispro in type 1 diabetic patients in a direct comparison and to investigate whether the administration of one analog results in favorable effects on prandial blood glucose control.

Research Design And Methods: A total of 24 type 1 diabetic patients (age 36 +/- 8 years, 16 men and 8 women, BMI 24.

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Motoring practices of diabetic drivers are similar to those of the average driving population. Due to the sudden onset of disabling hypoglycemia and the long-term complications of the disease, particularly retinopathy, one might assume that diabetic drivers are more prone to road traffic accidents than the average driver; however, the risk is not increased. The Council of the European Union recently laid down guidelines for dealing with this problem, which will lead to the introduction of a new law in Austria governing driving licensing.

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The efficacy of a treatment and teaching programme for non-insulin-treated Type 2 diabetic patients in general practice was evaluated in a prospective, controlled study. In a rural area in southern Austria, 53 patients from seven general practices participated in a structured programme (intervention group) and 55 patients from seven general practices without the programme served as the control group. After 6 months the weight reduction in the intervention group was 2.

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In 1989 representatives of all European governments agreed on the "St. Vincent Declaration". In this statement of intent and recommendations all governments, including that of Austria, pledged to implement policies on preventive measures geared to reduce morbidity and mortality of all diabetic patients in Europe.

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