Publications by authors named "Semin Ryu"

Background: Digital therapeutics are emerging as treatments for diseases and disabilities. In chronic kidney disease (CKD), gait is a potential biomarker for health status and intervention effectiveness. This study aims to analyze gait characteristics in CKD patients, providing baseline data for digital therapeutics development.

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Various sensing modalities, including external and internal sensors, have been employed in research on human activity recognition (HAR). Among these, internal sensors, particularly wearable technologies, hold significant promise due to their lightweight nature and simplicity. Recently, HAR techniques leveraging wearable biometric signals, such as electrocardiography (ECG) and photoplethysmography (PPG), have been proposed using publicly available datasets.

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Humans excel at determining the shape and material of objects through touch. Drawing inspiration from this ability, we propose a robotic system that incorporates haptic sensing capability into its artificial recognition system to jointly learn the shape and material types of an object. To achieve this, we employ a serially connected robotic arm and develop a supervised learning task that learns and classifies target surface geometry and material types using multivariate time-series data from joint torque sensors.

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One of the major reasons of mortality in human beings is cancer, and there is an absolute necessity for doctors to identify and treat a person suffering from it. Leukemia is a group of blood cancers that usually originates in the bone marrow and results in very high number of abnormal cells. For the diagnosis of cancer, microarray data serves as an important clinical application and serves as a great aid to the entire medical community.

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Manual sleep stage scoring is usually implemented with the help of sleep specialists by means of visual inspection of the neurophysiological signals of the patient. As it is a very hectic task to perform, automated sleep stage classification systems were developed in the past, and advancements are being made consistently by researchers. The various stages of sleep are identified by these automated sleep stage classification systems, and it is quite an important step to assist doctors for the diagnosis of sleep-related disorders.

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Disease symptoms often contain features that are not routinely recognized by patients but can be identified through indirect inspection or diagnosis by medical professionals. Telemedicine requires sufficient information for aiding doctors' diagnosis, and it has been primarily achieved by clinical decision support systems (CDSSs) utilizing visual information. However, additional medical diagnostic tools are needed for improving CDSSs.

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People who exercise may benefit or be injured depending on their foot striking (FS) style. In this study, we propose an intelligent system that can recognize subtle differences in FS patterns while walking and running using measurements from a wearable smartwatch device. Although such patterns could be directly measured utilizing pressure distribution of feet while striking on the ground, we instead focused on analyzing hand movements by assuming that striking patterns consequently affect temporal movements of the whole body.

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We propose an electromagnetic-based braille display that can represent two-dimensional information. The key principle is a flip-latch structure, which allows satisfying requirements of both protrusion force for braille recognition and low power consumption. A magnet-inserted flip-latch has an eccentric shape, and is driven by and flips over the protruded voice coil and pushing the braille pin.

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Inspired by spiders that can generate and sense vibrations to obtain information regarding a substrate, we propose an intelligent system that can recognize the type of surface being touched by knocking the surface and listening to the vibrations. Hence, we developed a system that is equipped with an electromagnetic hammer for hitting the ground and an accelerometer for measuring the mechanical responses induced by the impact. We investigate the feasibility of sensing 10 different daily surfaces through various machine-learning techniques including recent deep-learning approaches.

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Systemic air embolism through a bronchovenous fistula (BVF) has been described in patients undergoing positive-pressure ventilation. However, no report has mentioned the potential risks of systemic air embolism through a BVF in patients undergoing extracorporeal membrane oxygenation (ECMO). Positive-pressure ventilation and ECMO support in patients with lung injury can increase the risk of systemic air embolism through a BVF.

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Article Synopsis
  • L-carnosine, a dipeptide composed of β-alanine and histidine, has shown potential anti-tumor effects, particularly in colorectal cancer, though its molecular mechanisms were previously unclear.
  • Treatment with L-carnosine in HCT116 colorectal cancer cells led to decreased cell proliferation, arrested the cell cycle in the G0/G1 phase, and altered the expression of important cell cycle-related genes and proteins.
  • The study revealed that L-carnosine triggers cell cycle arrest and apoptosis by inhibiting the phosphorylation of key signaling pathways, specifically NF-κB and STAT1.
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Recently, various methods using, simultaneously, two types of tactile feedback have been proposed to emulate a real object. However, the possible masking effect when providing two types of tactile feedback has been scarcely reported. In this study, we investigated the masking effect caused by mechanical vibration on the perception of electrovibration.

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. In most reports on ECMO treatment, advanced age is classified as a contraindication to VA ECMO. We attempted to investigate whether advanced age would be a main risk factor deciding VA ECMO application and performing VA ECMO support.

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Background: Rapid influenza diagnostic tests (RIDTs) show variable sensitivities in clinical settings. We aimed to compare three digital RIDTs and one conventional RIDT.

Methods: We assessed 218 nasopharyngeal swabs from patients between neonates and 90 years old in 2016.

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Left ventricular thrombus is a common complication related to acute myocardial infarction. Removing this with an incision of the free wall of the left ventricle may cause fatal cardiac dysfunction or arrhythmias. Furthermore, performing incision and suture on the fragile myocardium of an acute myocardial infarction patient may cause serious bleeding complications.

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A 66-year-old male patient arrived at the emergency room with a crush injury to his chest. Multiple rib fractures, hemothorax on both sides, left scapular fracture, liver laceration, and retroperitoneal hematoma were found upon the radiologic examination. After closed thoracostomy, the patient had been initially admitted to the intensive care unit, but he was transferred to the general ward on the next day.

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Background: This paper aimed to verify the effects of renal replacement therapy on changing the levels of serum creatinine for different veno-arterial and veno-venous configurations in prolonged extracorporeal membrane oxygenation (ECMO) patients.

Methods: The subjects were chosen 71 patients who had undergone more than 1,440 minutes (24 hours) of the therapy from among 117 patients who had undergone ECMO insertion between January 2008 and December 2012. The patients were separated into the veno-arterial configuration group I (51 patients) and the veno-venous configuration group II (20 patients).

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Cigarette smoking (CS) is considered one of the major risk factors to cause neurodegenerative disorders. Nicotine is the main chemical in CS which is responsible for dysfunction of the brain as a neuroteratogen. Also, nicotine dependency is a real mental illness and disease.

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Infectious aortitis is a rare disease in the antibiotic era. Only a small number of cases of nonaneurysmal infectious aortitis are discussed in literature, and its true incidence and natural history are not well defined. We present here a case of typical nonaneurysmal infectious aortitis with literature review of 19 cases of aortic infection in which the aorta is initially normal in caliber.

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We report a case of 62-year-old man with cardiac tamponade due to coronary artery injury after acupuncture into the substernum. After resuscitation of cardiac arrest, we performed emergent pericardiocentesis. Nevertheless, the cardiac arrest recurred, and the emergent operation on cardiopulmonary bypass was performed.

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