Publications by authors named "Semiha Erisen"

Article Synopsis
  • The study investigates how eco-friendly silver nanoparticles (AgNPs) influence the production of secondary metabolites in Pimpinella anisum L. (anise), a plant whose metabolites are difficult to synthesize chemically.
  • Different concentrations of AgNPs were tested, showing that lower doses (1 and 5 mg/L) induced stress but ultimately led to increased production of essential fatty acids, while higher doses (10 and 20 mg/L) resulted in notable toxicity.
  • The findings suggest that AgNPs can effectively enhance the synthesis of valuable metabolites like omega fatty acids and phenolic compounds in anise, highlighting their potential as plant elicitors in agriculture and pharmaceuticals.
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Despite its evidenced beneficial herbicidal, antibacterial, antiviral, antifungal, and antioxidant effects, the application of juglone (5-hydroxy-1,4,-naphthoquinone) is limited due to its low water solubility and allelopathic and toxic effects. In recent years, research has aimed to overcome these limitations by increasing its solubility and controlling its release through nanoparticular systems. This is the first study to have synthesised and characterised juglone-loaded polymeric nanoparticles and compared them with free juglone for cytotoxicity in mouse (L929 fibroblasts) and alfalfa cells and for mutagenic potential in Salmonella typhimurium TA98/100.

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