Comparison of submucosal resection and radiofrequency turbinate volume reduction for inferior turbinate hypertrophy: evaluation by magnetic resonance imaging.

Inferior turbinate hypertrophy is a frequent cause of nasal airway obstruction and drastically impairs patients' quality of life. Surgical reduction of the inferior turbinates can be used for patients who did not respond to medical therapy. A number of studies have been performed to identify the most effective technique.

Comparison of clinical differences between patients with allergic rhinitis and nonallergic rhinitis.

We conducted a retrospective study to investigate the clinical differences between subtypes of rhinitis patients. Our findings were based on a detailed history and nasal examination. The study population was made up of 910 patients who had at least two rhinitis symptoms.

Histopathologic parameters in chronic rhinosinusitis with nasal polyposis: impact on quality of life outcomes.

Background: Chronic rhinosinusitis (CRS) is a common disease with a significant impact on health-related quality of life (QOL) of the patient. Histologic inflammatory markers in CRS are an important marker in determining the severity of the disease. In this study, we evaluated the association of histopathologic parameters with QOL questionnaires in patients with CRS with nasal polyposis after endoscopic sinus surgery (ESS).

Complications of tracheoesophageal puncture and speech valves: retrospective analysis of 47 patients.

Objectives: This study aims to evaluate the complications of tracheoesophageal puncture (TEP) for voice restoration and speech valves in patients undergoing total laryngectomy.

Patients And Methods: Between January 2006 and June 2011, 47 male patients (mean age 62.8±1.

Recovery of hearing in Cisplatin-induced ototoxicity in the Guinea pig with intratympanic dexamethasone.

The purpose of this study was to investigate the effectiveness of intratympanic dexamethasone injection as a therapeutic agent against cisplatin-induced ototoxicity. Animals were randomly divided into three groups. Group one received intraperitoneal cisplatin alone, group two, received intratympanic dexamethasone after cisplatin ototoxicity had been demonstrated.

Endonasal endoscopic approach for recurrent nasolabial cyst.

Nasolabial cysts are rare nonodontogenic cystic lesions in the soft tissue of the midface and usually present with painless asymptomatic swelling in the nasolabial region. Surgical excision via sublabial approach is considered as the standard treatment. However, endonasal endoscopic marsupialization of the cyst is reported as an effective alternative method for nasolabial cysts.

Supracricoid partial laryngectomy: analyses of oncologic and functional outcomes.

Objective: The aim of this study was to analyze the functional and oncologic results of supracricoid partial laryngectomy.

Study Design: Case series with chart review.

Setting: Katip Celebi University Ataturk Training and Research Hospital, Izmir, Turkey.

Evaluation of p53, p63, p21, p27, ki-67 in paranasal sinus squamous cell carcinoma and inverted papilloma.

Using a molecular genetic approach, we try to confirm the molecular alterations of inverted papilloma and clarify its status as a putative precursor lesion of sinonasal squamous cell carcinoma. To better understand its genetics, we investigated the immunohistochemical protein expression patterns of cell-cycle-regulators p53, p63, p21, p27 and proliferation marker Ki-67 in 22 inverted papilloma and 9 squamous cell carcinoma of the sinonasal tract. Significantly elevated levels of p53 and p63 in squamous cell carcinoma of sinonasal tract compared with inverted papilloma were revealed.

[Approaches to antrochoanal polyps in adults: long-term comparative results].

Objectives: This study aims to evaluate the long-term results of endoscopic sinus surgery and combined approach with Caldwell Luc procedure for the treatment of antrochoanal polyps.

Patients And Methods: Between January 2002 and December 2009, 41 patients (24 males, 17 females; mean age 34.7 years; range 14 to 78 years) were retrospectively analyzed.

ETS-1 proto-oncogene as a key newcomer molecule to predict invasiveness in laryngeal carcinoma.

ETS-1 protein is one of the key regulators in tumor invasion and progression. We aimed to evaluate the role of ETS-1 in the invasiveness and progression of laryngeal squamous carcinoma, as well as to determine the correlations between clinicopathological characteristics and expression of this molecule. We assessed the levels of ETS-1 in a total of 96 laryngeal specimens of varying degrees of dysplasia, microinvasive squamous carcinoma (8), and invasive squamous carcinoma (60), using normal mucosal epithelium (10) as a positive control.

Perichondrium/Cartilage island flap and temporalis muscle fascia in type I tympanoplasty.

Objective: To compare the functional results of primary type I tympanoplasty performed with temporalis muscle fascia and a perichondrium/cartilage island flap.

Design: Retrospective chart review.

Setting: Research and training hospital.

Pharyngocutaneous fistula after total laryngectomy: Less common with mechanical stapler closure.

Objectives: The aim of the study was to compare the incidences of pharyngocutaneous fistula after total laryngectomy between patients who underwent manual and mechanical suturing for pharyngoesophageal closure.

Methods: In a retrospective and prospective nonrandomized clinical study conducted at a single tertiary medical center between May 2002 and April 2009, we compared the incidence of pharyngocutaneous salivary fistula between two groups of patients after total laryngectomy. Sixty-one consecutive patients who underwent mechanical suturing with a 60-mm linear stapler (group A) were prospectively enrolled, and 121 patients who had undergone manual suturing (group B) were retrospectively reviewed.

[The evaluation of cordectomy cases without tracheotomy in laryngeal cancer].

Objectives: We evaluated the technique of laryngofissure cordectomy without tracheotomy in patients with T1a laryngeal carcinoma.

Patients And Methods: Twelve male patients (mean age 55 years; range 47 to 68 years) who were diagnosed with T1a laryngeal carcinoma and treated with cordectomy without tracheotomy between January 2005 and March 2008 in our clinic were evaluated with retrospective review of medical charts. They were all treated with laryngofissure and cordectomy.

Measurements of the facial recess anatomy: implications for sparing the facial nerve and chorda tympani during posterior tympanotomy.

Posterior tympanotomy is commonly performed through the facial recess to facilitate cochlear implantation. A rare but serious complication of this procedure is paralysis of the facial nerve and/or the chorda tympani. These complications generally occur because of a limited understanding of the anatomy of the facial recess.

Evaluation of bacterial biofilms in chronic rhinosinusitis.

Objective: We investigated the presence of biofilms in patients with chronic rhinosinusitis.

Design: Prospective study.

Methods: Thirty patients with chronic rhinosinusitis scheduled for endoscopic sinus surgery were enrolled in this study.

[Evaluation of superior semicircular canal dehiscence in patients with vertigo and tinnitus].

Objectives: The aim of the study was to investigate the presence of superior semicircular canal dehiscence (SSC) in patients with unknown etilogy of vertigo/tinnitus.

Patients And Methods: This study was performed prospectively between December 2007 and March 2008. Fifty five patients (23 males, 32 females; mean age 44.

[Evaluation of depth of invasion and tumor diameter in relation to tumor localization in laryngeal cancer].

Objectives: We investigated the relationship between tumor localization and depth of tumor invasion and tumor diameter.

Patients And Methods: Neck dissection specimens of 70 patients (mean age 61+/-10 years, range 38 to 77 years) who underwent laryngectomy for squamous cell carcinoma of the larynx were histopathologically re-examined with regard to the number and localization of metastatic lymph nodes, depth of tumor invasion, and tumor diameter. Three tumor groups (supraglottic, glottic, and transglottic) were compared with respect to depth of tumor invasion, tumor diameter, metastatic lymph nodes, and T-stage.

Pharyngocutaneous fistula after total laryngectomy: emphasis on lymph node metastases as a new predisposing factor.

Objective: We investigated patient-related and local risk factors for pharyngocutaneous fistula developing after total laryngectomy.

Design: Retrospective clinical study.

Setting: Tertiary medical centre.

Effectiveness of royal jelly on tympanic membrane perforations: an experimental study.

Objective: The aim of this study was to evaluate the comparison of the efficacy of royal jelly in a guinea pig tympanic membrane perforation model with untreated and control groups.

Study Design: Prospective study using 16 adult guinea pigs.

Methods: Each animal underwent subtotal removal of the tympanic membrane in one ear.

Preoperative clinical prediction of difficult laryngeal exposure in suspension laryngoscopy.

We investigated general and physical predictors of difficult laryngeal exposure in patients undergoing suspension laryngoscopy; 93 patients were included in this prospective study. The patients were classified as difficult laryngeal exposure group or non-difficult laryngeal exposure group based on the laryngeal view in suspension laryngoscopy. Twelve parameters (age, sex, body mass index, neck circumference, full mouth opening, modified mallampati index, hyoid-mental, thyroid-mental, horizontal thyroid-mental, vertical thyroid-mental, sternum-mental distance) that could predict difficult laryngeal exposure were evaluated.

Evaluation of prognostic factors and middle ear risk index in tympanoplasty.

Objective: The aim of this study was to examine the role of the prognostic factors and middle ear risk index on the success of tympanoplasty.

Study Design: Case series.

Subjects And Methods: The charts of 231 patients who underwent tympanoplasty operations between 2002 and 2007 were reviewed.

[Pharyngocutaneous fistula after total laryngectomy: incidence and analysis of risk factors].

Objectives: We evaluated the incidence and predisposing risk factors of pharyngocutaneous fistulas that develop after total laryngectomy.

Patients And Methods: The records of 210 patients (19 females, 191 males; mean age 60+/-9 years; range 39 to 77 years) who underwent total laryngectomy were retrospectively reviewed. Thirteen predisposing risk factors were evaluated (age, sex, pre-and postoperative anemia and hypoalbuminemia, diabetes mellitus, coronary artery disease, chronic obstructive pulmonary disease, hypertension, preoperative tracheotomy, tumor stage and localization).

Predictors of extracapsular spread in lymph node metastasis.

We investigated effect of clinical and pathologic parameters on extracapsular spread (ECS) in patients with lymph node metastasis in laryngeal and hypopharyngeal cancer. About 186 patients and 342 neck dissection were included in this study. Relationship between ECS and tumor location, T stage, pathologic N stage, tumor differentiation, number of metastatic lymph nodes, diameter of metastatic lymph node and impact of presence ECS on contralateral neck metastasis (CNM) were evaluated; 76 of the 186 patients had lymph node metastasis.

Efficacy of nasal corticosteroids alone or combined with antihistamines or montelukast in treatment of allergic rhinitis.

Objective: Topical corticosteroids are recommended as initial therapy in allergic rhinitis (AR) patients. We investigated clinical efficacy of monotherapy with topical steroid and combined therapy in AR patients.

Methods: Ninety-five AR patients sensitive to grass pollens according to skin prick test results were enrolled in this placebo-controlled and open study.