Publications by authors named "Sema-Hayriye Sivritas"
Article Synopsis
- - Neph proteins are crucial membrane proteins involved in creating specific cell contacts and play important roles in various biological processes like eye development in fruit flies, neural connections in roundworms, and kidney function in mammals.
- - The study identifies PICK1 as a protein that interacts with Neph proteins, with its binding requiring dimerization and dependent on interactions with other PDZ domain proteins, stabilizing Neph1 at the cell membrane.
- - In experiments with fruit flies, reducing PICK1 levels led to a destabilization of the Neph homologue Roughest, which disrupted eye development, highlighting the cooperative role of Neph proteins and PICK1 in cell recognition.
Blockade of renal medullary bradykinin B2 receptors increases tubular sodium reabsorption in rats fed a normal-salt diet.
Am J Physiol Renal Physiol
September 2008
The present study was performed to test the hypothesis that under normal physiological conditions and/or during augmentation of kinin levels, intrarenal kinins act on medullary bradykinin B(2) (BKB(2)) receptors to acutely increase papillary blood flow (PBF) and therefore Na(+) excretion. We determined the effect of acute inner medullary interstitial (IMI) BKB(2) receptor blockade on renal hemodynamics and excretory function in rats fed either a normal (0.23%)- or a low (0.
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