Publications by authors named "Sema Kaya"
Purpose: Hydrogels derived from decellularized tissues are promising biomaterials in tissue engineering, but their rapid biodegradation can hinder in vitro cultivation. This study aimed to retard biodegradation of a hydrogel derived from porcine decellularized lacrimal glands (dLG-HG) by crosslinking with genipin to increase the mechanical stability without affecting the function and viability of lacrimal gland (LG)-associated cells.
Methods: The effect of different genipin concentrations on dLG-HG stiffness was measured rheologically.
Objective: The aim of this study is to determine the age-based prevalence of dens invaginatus cases and to learn the radiologic findings. In addition, fractal analysis of the periapical regions of unilateral dens invaginatus cases and contralateral teeth was performed to determine the effect of possible microleakage on fractal dimension.
Methods: A total of 136 patients (170 teeth) identified in panoramic radiographs taken for diagnostic purposes between January 2018 and December 2023 at our Department of Oral and Maxillofacial Radiology were included in the study.
Article Synopsis
- Sustainable treatment for aqueous deficient dry eye (ADDE) is lacking, necessitating new strategies like tissue-specific hydrogels that mimic the extracellular matrix to support cell function.
- Researchers developed a decellularized lacrimal gland hydrogel (dLG-HG) that maintains the necessary biochemical properties, showing improved cell proliferation and secretion capabilities compared to standard culture substrates like Matrigel and collagen type-I.
- While dLG-HG promotes vital cell interactions and functions, its rapid biodegradation poses challenges for long-term cultivation, indicating a need for further research to slow this process.
Article Synopsis
- - The study utilized a tree-like graph structure to represent the diverse characteristics of type 2 diabetes, analyzing 927 participants with recent-onset diabetes to identify key health factors and complications over time.
- - Participants were evaluated on clinical and laboratory measures, including insulin sensitivity and secretion, and factors such as hepatic lipid content and inflammatory biomarkers were linked to different progression outcomes in diabetes.
- - Findings revealed that lower insulin sensitivity correlated with higher liver fat, inflammation, and cardiovascular risk, while lower insulin secretion was associated with greater need for insulin therapy and increased chance of diabetic neuropathy.
According to the common opinion in the literature, the sustainability of container ports is a tremendously complex topic owing to the maritime sector's excessively dynamic form and many highly complex, predictable and unpredictable uncertainties in this industry. The current paper proposes two powerful, practical, inspiring approaches to fill these gaps. It proposes a novel type-2 neutrosophic fuzzy numbers (T2NFNs) based Delphi method to determine the criteria logically and optimal and extends the WASPAS technique based on the T2NFNs for evaluating the alternatives.
View Article and Find Full Text PDFIntroduction: This study aimed to evaluate the possible effects of maxillary molar distalization on maxillary sinus mucosa thickness and sinus volume in 3-dimensions.
Methods: The study was conducted with 46 patients: 73.9% (n = 34) females and 26.
Article Synopsis
- Nearly half of astronauts experience "Spaceflight associated neuro-ocular syndrome" (SANS) after long-duration missions, with the exact causes still unclear.
- This study will involve healthy subjects undergoing parabolic flights that simulate microgravity to investigate changes in retinal blood circulation using advanced imaging techniques.
- By examining retinal vessel changes and measuring intra-ocular pressure during these flights, the research seeks to determine if these factors play a role in the development of SANS.
A novel two-phase group decision-making model for circular supplier selection under picture fuzzy environment.
Environ Sci Pollut Res Int
March 2023
Circular supply chain management (CSCM), which incorporates circular thinking into supply chain management, promotes supply chain sustainability by offering a novel and compelling viewpoint. In the CSCM, supplier selection is crucial in establishing a competitive edge among businesses by decreasing environmental degradation and related supply chain expenses. This paper aims to propose a novel two-phase group decision-making approach, which combines the picture fuzzy Analytical Hierarchical Process (PF-AHP) and grey Measurement of Alternatives and Ranking According to Compromise Solution (MARCOS-G) model to select railway material suppliers within the scope of circular economy perspective.
View Article and Find Full Text PDFObjectives: This study aimed to analyze the association between the use of proton pump inhibitors (PPIs) and radiomorphometric parameters of trabecular and cortical bone of the mandible.
Methods: A total of 64 patients (37 females and 27 males) using PPIs (PPI group) and 64 age- and gender-matched healthy individuals (control group) were included in this study. The analyzed radiomorphometric parameters were fractal dimension (FD), mandibular cortical width (MCW), and mandibular cortical index (MCI).
Purpose: The aim of this study was to determine the prevalence of canine transmigration in the maxilla and mandible and to perform a 3-dimensional examination of impacted canines (ICs) on cone-beam computed tomography (CBCT) images.
Materials And Methods: CBCT images of 35 transmigrated and 35 nontransmigrated canines (control group) were analyzed. Associations between gender, jaw, dental anomalies associated with ICs, adjacent lateral status, the status of deciduous canine, contact of the apical region with the cortex, contact of the crown with the cortex, canine location, resorption of adjacent teeth and severity, periodontal contour of adjacent teeth, odontoma, root status of the canine, cyst formation, and age groups of patients with transmigration were evaluated.
Objectives: The purpose of this study was to evaluate the effect of section thickness on volume estimations of bone defects scanned using cone beam computed tomography (CBCT).
Methods: 25 bone defects were prepared on sheep mandibles and scanned using a KaVo 3D eXam (KaVo Dental, Biberach, Germany) CBCT device. Section thickness of images were reconstructed at 0.
Purpose: The study examined the association between mastoid pneumatization (MP) volume and the existence of foramen Huschke (FH).
Methods: Cone beam computed tomography (CBCT) images of 1117 patients (2234 mastoid regions) were analyzed. The prevalence of FH was calculated.
Red blood cells (RBCs) play an important role in the cardiac ischemia/reperfusion (I/R) injury. Cardiovascular risk factors impair the RBC function in an endothelial nitric oxide synthase (eNOS) dependent manner. However, it is unclear whether the protective role of RBCs can be rescued by modifying cardiovascular risk factors or by pharmacologic intervention.
View Article and Find Full Text PDFIntroduction: Myocardial infarction is one of the leading causes of morbidity and mortality worldwide. Cellular interactions of red blood cells (RBCs) and platelets with endothelial cells and cardiomyocytes play a crucial role in cardiac ischemia/reperfusion (I/R) injury. However, addressing the specific impact of such cell-to-cell interactions in commonly employed in vivo models of cardiac I/R injury is challenging due to overlap of neuronal, hormonal, and immunological pathways.
View Article and Find Full Text PDFBackground: In weightlessness, alterations in organ systems have been reported. The microcirculation consists of a network of blood vessels with diameters of a few μm. It is considered the largest part of the circulatory system of the human body and essential for exchange of gas, nutrients and waste products.
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