Synthesis of Carbon Dots via Microwave-Assisted Process: Specific Sensing of Fe(III) and Antibacterial Activity.

Carbon dots synthesized from a renewable and sustainable source of biomass have greater attention in the nanomaterial research field. In the present study, we adopted a facile and green synthesis of carbon dots from bio waste of pumpkin seeds using a one-pot microwave-assisted carbonization method. The synthesized carbon dots exhibit excellent photoluminescence properties with a bright blue emission peak at 399 nm and fluorescence quantum yield was about 9.

Harnessing the ocean's pharmacy: marine bioactive compounds as next-generation therapeutics.

The ocean's vast and diverse ecosystem offers a rich reservoir of bioactive compounds with immense clinical potential. Marine organisms produce structurally unique and biologically active compounds, leading to breakthroughs in therapeutic development. Notable examples include anticancer agents like trabectedin and cytarabine, and the analgesic ziconotide.

Eco-friendly and sustainable process for recovery of sulfate from paper mill mixed salt: Recycling of sulfate for dye fixation process.

Paper mill Electrostatic Precipitator (ESP) ash contains a mixture of alkali metal chloride (34.2 %) and sulfate (84.2 %) which has serious negative effects on the environment and makes it more expensive and constrained to dispose ESP ash.

An impactful prospective study on pulmonary tuberculosis in geriatric populations besides its clinical outcomes and implications in the Indian subcontinent.

Objective: Geriatric populations are most at risk for the tuberculosis pandemic, and as people age, the rate of infection rises steadily and drastically. Geriatric individuals frequently experience diagnostic challenges with a wide range of comorbidities, but employing all available standard and novel methods to diagnose any infection is crucial. The prophylactic and therapeutic management for the geriatric population presents a significant difficulty and challenge in assessing an appropriate and effective therapeutic outcome due to prolonged drug therapy and adverse drug reactions.

Scanning Electron Microscopic Analysis of Deformation of TruNatomy File Systems: An Ex-vivo Study.

Aim The aim of the study was to assess the instrument deformation following the usage of the TruNatomy (Dentsply Sirona, USA) file system in extracted premolars using Scanning Electron Microscopy (SEM). Materials and Methods For the present study, 84 extracted mandibular bicuspids were selected. The teeth were divided into two groups: Group 1, TruNatomy (n=42), and Group 2, Hero Shaper (Micro Mega, France) (n=42).

Prevalence of Depression and Anxiety Disorders Among Cancer Patients: An Insight From a Single Institute.

Objective This cross-sectional, observational study aimed at finding the prevalence of anxiety and depression in cancer patients and the correlation of anxiety and depression with various factors, such as age, sex, marital status, educational status, occupation, financial support, duration, type of care, sort of carcinoma, and stages of malignancy, among cancer patients attending the G. Kuppuswamy Naidu Memorial Hospital, Coimbatore, Tamil Nadu, India from July 2022 to December 2022, using the Hospital Anxiety and Depression Scale (HADS). Methods A total of 162 cancer patients referred for various cancer therapies (chemo/surgery/combination therapies) were included.

Fracture Resistance of Endodontically Treated Teeth Restored With Short Fiber Reinforced Composite and a Low Viscosity Bulk Fill Composite in Class II Mesial-Occlusal-Distal Access Cavities: An Ex-vivo Study.

Background Teeth undergoing endodontic therapy are prone to structural weakening and increased risk of fractures. The absence of marginal ridges and pericervical dentin further compromises the fracture resistance. The choice of the post-endodontic coronal seal is crucial for the effectiveness of endodontic therapy.

Systematic review fracture resistance of endodontically treated posterior teeth restored with fiber reinforced composites- a systematic review.

Background: Large cavity designs and access cavities impair endodontically treated tooth fracture resistance. As the tooth's strength is known to reduce significantly after the root canal treatment, occlusal loading as a result of functions such as chewing, biting and certain parafunctional tendencies makes the endodontically treated tooth vulnerable to fracture. Hence, after endodontic treatment, it is vital to give adequate and appropriate restorative material to avoid tooth fractures.

Diabetes and TB: Confluence of Two Epidemic and Its Effect on Clinical Presentation.

Background: Tuberculosis (TB) has become a rising concern in low-income countries, particularly in those with Human Immuno Deficiency Virus (HIV) epidemics, and type 2 diabetes has emerged as a significant global chronic health problem, owing to increases in obesity, lifestyle changes, and ageing populations. Diabetes has been identified as a major risk factor for the development of TB. Despite the fact that diabetes imparts a substantially lower risk of TB (3-fold) as compared to HIV (>20-fold), in communities where the number of DM patients is high, the contribution of diabetes to TB might be bigger than HIV.

Evaluation of Endpoints Used in Clinical Trials on Adenomyosis - A Systematic Review.

Adenomyosis lacks approved pharmacological treatment even after decades of its identification. We performed this study to review the status of clinical research on adenomyosis for finding an effective drug therapy and to identify the most common endpoints used in adenomyosis trials. A systematic search was performed in the PubMed and Clinicaltrials.

Possibility of averting cytokine storm in SARS-COV 2 patients using specialized pro-resolving lipid mediators.

Fatal "cytokine storms (CS)" observed in critically ill COVID-19 patients are consequences of dysregulated host immune system and over-exuberant inflammatory response. Acute respiratory distress syndrome (ARDS), multi-system organ failure, and eventual death are distinctive symptoms, attributed to higher morbidity and mortality rates among these patients. Consequent efforts to save critical COVID-19 patients via the usage of several novel therapeutic options are put in force.

Hydroxychloroquine plus personal protective equipment versus personal protective equipment alone for the prevention of laboratory-confirmed COVID-19 infections among healthcare workers: a multicentre, parallel-group randomised controlled trial from India.

Objectives: To determine whether hydroxychloroquine when used with personal protective equipment reduces the proportion of laboratory-confirmed COVID-19 among healthcare workers in comparison to the use of personal protective equipment alone.

Design: Multicentre, parallel-group, open-label randomised trial. Enrolment started on 29 June 2020 and stopped on 4 February 2021.

Critical Clinical Evaluation of COVID-19 Patients with Tuberculosis in the Indian Sub-Continent.

Background: COVID-19 and tuberculosis (TB) are infectious diseases that predominantly affect the respiratory system with common symptoms, such as cough, fever, and shortness of breath, making them dual burdens.

Methods: This review will discuss the characteristics of the coexistence of TB and new infectious illnesses to provide a framework for addressing the current epidemic. Currently, there are no clear and significant data on COVID-19 infection in TB patients, they may not respond appropriately to drug therapy and may have worse treatment outcomes, especially if their TB treatment is interrupted.

Electrochemical oxidation with the aerobic pretreatment process for sulfate-rich tannery effluent.

The anaerobic feed of tannery effluent was treated using a new invention of an integrated approach: electrochemical oxidation with aerobic pretreatment, which reduces the chemical oxygen demand (COD) and sulfur/sulfide gas formation. Bacterial consortium was used in the present study isolated from a common effluent treatment plant (CETP). Microbial community analysis of anaerobic feed of tannery effluent (AFTE) was done by next generation sequencing.

An integrated (electro- and bio-oxidation) approach for remediation of industrial wastewater containing azo-dyes: Understanding the degradation mechanism and toxicity assessment.

A hybrid approach for the remediation of recalcitrant dye wastewater is proposed. The chlorine-mediated electrochemical oxidation of real textile effluents and synthetic samples (using Ti/IrO2-RuO2-TiO2 anodes), lead to discoloration by 92% and 89%, respectively, in 100min, without significant mineralization. The remediation was obtained through biodegradation, after removing the residual bio-toxic active chlorine species via sunlight exposition.