Publications by authors named "Selvamani Muthamizh"

Introduction Dopamine serves an essential function as a neurotransmitter, influencing the regulation of movement, cognitive processes, and emotional states. The identification of abnormal dopamine levels is critical for clinical diagnoses and scientific research, given its links to various disorders, including depression, schizophrenia, and Parkinson's disease. The distinctive electrochemical characteristics, stability, and broad bandgap of zinc sulfide (ZnS) nanostructures render them particularly fascinating.

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Article Synopsis
  • - The study focuses on synthesizing manganese(III) oxide (MnO), characterizing its structure, and analyzing its electrochemical properties, particularly in relation to dopamine detection, which is significant for medical diagnostics.
  • - MnO is synthesized using manganese sulfate and potassium permanganate in deionized water, followed by a series of heating and drying processes in a sealed autoclave to form hierarchical rod-like structures.
  • - Characterization techniques such as X-ray diffraction (XRD) and field emission scanning electron microscopy (FE-SEM) confirm the crystalline structure and 100 nm particle size of MnO, while cyclic voltammetry tests indicate improved sensing ability of the modified electrode compared to a bare electrode.
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Background  The article delineates a strategy for detecting ascorbic acid (AA) through the use of iron oxide (Fe₂O₃) nanoparticles on an electrode. The Fe₂O₃ nanoparticles demonstrated effective electrocatalysis in the oxidation of AA, resulting in increased peak currents. The sensor showcased a wide linear detection range, a low detection limit, and high selectivity towards interferents, making it suitable for accurate AA measurement in food analysis and medical diagnostics applications.

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Background In recent years, significant advancements have been made in various scientific sectors, particularly in healthcare and pharmaceutical research. This progress has been driven by the development of enhanced sensing materials and methodologies. Electrochemical sensing has become an important tool in detecting and analyzing drug molecules due to its high sensitivity, specificity, and rapid response times.

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Article Synopsis
  • - This study investigates the anti-metastatic effects of a flowering plant known as wild heliotrope on MCF-7 breast cancer cells, focusing on its ability to disrupt key signaling pathways.
  • - Using an MTT assay, the research found that the plant extract significantly inhibited cell growth, with maximum inhibition observed at a concentration of 150 μg/mL, and it suppressed important pathways like GSK3β and Wnt2.
  • - The findings suggest that the plant may serve as a potential anticancer agent against breast cancer, indicating further evaluation could be beneficial for different breast cancer types and cell lines.
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The synthesis of InVO-CdS heterojunction photocatalysts has been achieved by a novel two-step approach, including a microwave-assisted technique, followed by a moderate hydrothermal method, marking the first successful instance of such a synthesis. X-ray diffraction, field-emission scanning electron microscopy, elemental color mapping, high-resolution transmission electron microscopy, UV-vis diffuse reflectance spectroscopy, Raman analysis, photoluminescence, X-ray photoelectron spectroscopy, and Brunauer-Emmett-Teller were employed to investigate the crystal structures, surface morphologies and particle sizes, chemical compositions, and optical characteristics of the as-synthesized materials. The research results indicated that the heterojunction InVO-CdS, as synthesized, consisted of InVO microrods with an average size of around 15 nm and cadmium sulfide (CdS) microflowers with a diameter of 1.

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Background Electrochemical sensing is a versatile field that uses electrochemistry concepts to detect and measure various substances. It finds applications in clinical diagnostics and environmental monitoring. Scientists are currently working on creating reliable electrochemical sensing devices that can accurately detect ascorbic acid.

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Background: The pressing need for precise, quick, and affordable detection of diverse biomolecules has led to notable developments in the realm of biosensors. Quercetin, a biomolecule rich in flavonoids predominantly found in our diet, is sensed by the electrochemical method. The electrochemical properties show remarkable improvement when MnO (MO) is doped with cobalt (Co).

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Background This study investigates 's curative effectiveness against colon cancer cells. , often known as Elika jemudu, is a Convolvulaceae family plant. The inhibitory ability of anticancer herbal extracts against cancer cell growth and mediators is tested.

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This article describes an affordable method for the synthesis of MnMoO nanoflowers through the microwave synthesis approach. By manipulating the reaction parameters like solvent, pH, microwave power, and irradiation duration along this pathway, various nanostructures can be acquired. The synthesized nanoflowers were analyzed by using a powder X-ray diffractometer (XRD), field emission scanning electron microscopy (FE-SEM) with energy dispersive X-ray spectroscopy (EDS), Fourier transform infrared spectroscopy (FT-IR), and UV-vis diffuse reflectance spectroscopy (UV-DRS) to determine their crystalline nature, morphological and functional group, and optical properties, respectively.

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Background:  An assessment of extract's antimicrobial and antioxidant properties was undertaken in light of its possible application as an oral care product. The maintenance of optimal dental health is just as important as overall wellness. Food particles become trapped in the mouth cavity, making it easy for oral bacteria to infect.

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Increasing resistance of pathogens and cancer cell line towards antibiotics and anticancer agents has caused serious health problems in the past decades. Due to these problems in recent years, researchers have tried to combine nanotechnology with material science to have intrinsic antimicrobial and anticancer activity. The metals and metal oxides were investigated with respect to their antimicrobial and anticancer effects towards bacteria and cancer cell line.

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A poly(methylene blue)-modified glassy carbon electrode (PMB/GCE) was fabricated by electropolymerisation of methylene blue on a GCE and further utilized to investigate the electrochemical determination of 4-nitrophenol (4-NP) by cyclic voltammetry (CV), differential pulse voltammetry and chronocoulometry. The morphology of the PMB on GCE was examined using a scanning electron microscope (SEM). An oxidation peak of 4-NP at the PMB modified electrode was observed at 0.

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