Histamine release from leucocytes in migraine.

The spontaneous histamine release (SHR) from leucocytes in migraine patients during symptom-free periods has been investigated, and also the influence of migraine sufferer serum on histamine release (HR) from blood donor leucocytes. The leucocytes were isolated according to the Day method and histamine assay was made by the Shore spectrofluorometric method modified by Bergendorff and Uväs (1). SHR in the 17 female migraine patients was significantly higher (39.

[Diurnal rhythm of the bioelectrical activity of the brain and blood serotonin level in patients with migraine].

Investigations of biological rhythms were done in migraine relating the results to certain neurochemical and electroencephalographic studies. The obtained results demonstrated evident individual fluctuations of blood serotonin level in patients with migraine and in control groups. Correlations and connections were demonstrated between the blood serotonin level and EEG pattern and type of migraine.

[Incidence of migraine among physicians of the city of Lódź and their families].

Using an inquiry method the prevalence of migraine was determined in a group of 711 physicians and their spouses in the City of Lódź. This prevalence was 7.8%-12.

[Blood serotonin level in sciatica and the serotonin theory of migraine pathogenesis].

The blood serotonin level was determined by the fluorescent method of Ashcroft in 13 patients with sciatic pains during the pains and after the disappearance. The serotonin level was usually higher at the time of pains. In the discussion the author reminds that serotonin level falls during a migrainous attack and points out that the results of the present study confirm the specificity of sertonin level fall in migraine.