[The status of adaptive-compensatory mechanisms after the brain concussion in children].

80 children of preschool age were observed after concussion of the brain. In follow-up from 6 months 3 years clinical-anamnestic and neuropsychologic methods were used. The functions of autonomic nervous system were evaluated according to the results of estimation of initial autonomic tonus, autonomic reactivity, autonomic maintenance of the activity and the data of cardiointervalography.

[Autonomic regulation in the acute period of tick-borne encephalitis in children].

The clinico-epidemiological analysis and comparison of the data of a comprehensive study of suprasegmental vegetative regulation revealed an appreciable tension of the adaptation mechanisms in the acute period in 55 children with the meningeal form of tick-borne encephalitis (TE). Alterations in vegetative regulation in children suffering from TE were found to be coupled with impairment of the stem-hemispheric interrelations, reduction in the level of nonspecific activation, rise of convulsive preparedness of the brain. A correlation was established between alterations in the main parameters of variational cardiointervalography, character of brain bioelectric activity and the disease gravity.

[Mechanisms of the development of autonomic regulation disorders in neurogenic syncope in childhood].

Based on a clinico-anamnestic analysis and comparison of the data of comprehensive studies of vegetative nervous system functions it was discovered that in 85 children aged 4 to 14 years suffering from neurogenous syncopes, vegetovascular maintenance of the processes of activation and adaptation turned out insufficient. It is shown that in early childhood, the formation of vegetative dysregulation occurs under the influence of numerous factors, of which the most significant are hereditary predisposition to paroxysms, perinatal pathology, and psychogenic effects. It is established that there are two possible variants of the combination of pathophysiological alterations predetermining the clinical picture and phenomenology of neurogenous syncopes in children.

[Rhythm of the daily changes in functions in ischemic heart disease].

The daily changes in the functional state of the cardiovascular system and in the indices of bioelectric activity and hemodynamics of the brain, as well as the daily variability of lipid metabolism, electrolytes and 17-OCS in urine and certain indices of hemostasis were studied in 162 patients with ischemic heart disease. It was shown that, as compared to healthy individuals, patients with ischemic heart disease had a smaller amplitude of fluctuations in the daily rhythm with displacement of the peaks of activity to a later time. The only exception was the daily excretion of 17-OCS and aldosterone, the amplitude of fluctuations of which was close to that of these indices in healthy individuals but was distinguished by a displacement of 4 hrs.

[Rhythm of the daily fluctuations in lipid metabolic and fibrinolysis system indices in ischemic heart disease].

The study was conducted on 22 patients with ischemic heart disease (I stage atherosclerosis according to the classification suggested by A. L. Myasnikov).