Characterization of Beta-Lactam Resistome of Causing Nosocomial Infections.

Nosocomial infections caused by pose significant therapeutic challenges due to the high expression of genes encoding antimicrobial drug resistance. In this study, we investigated the conformation of the beta-lactam resistome responsible for the specific pattern of resistance against beta-lactam antibiotics. A total of 218 strains were isolated from in-hospital patients diagnosed with nosocomial infections, obtained from various sources such as urine ( = 49, 22.