Publications by authors named "Selena Gonzales"
Background: There is no FDA-approved left ventricular assist device (LVAD) for smaller children permitting routine hospital discharge. Smaller children supported with LVADs typically remain hospitalized for months awaiting heart transplant-a major burden for families and a challenge for hospitals. We describe the initial outcomes of the Jarvik 2015, a miniaturized implantable continuous flow LVAD, in the NHLBI-funded Pumps for Kids, Infants, and Neonates (PumpKIN) study, for bridge-to-heart transplant.
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- * The study involves children under 21 years old, randomizing them at 6 months post-transplant for a 30-month follow-up, aiming to determine which immunosuppression regimen is more effective at preventing acute cellular rejection, chronic kidney disease, and cardiac allograft vasculopathy.
- * The trial's primary endpoint is the MATE score, which measures the frequency and severity of major adverse transplant events, and is designed
Although it is known that children undergoing heart transplantation are at increased risk for both AKI and CKD, renal function following CHLT remains understudied. All pediatric CHLT patients from 2006 to 2019 were included. The prevalence of AKI in the first 7 post-operative days, renal recovery at 30 post-operative days, and CKD were ascertained.
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