Publications by authors named "Selen Yilmaz"
Objective: To determine the effect of online sustainable nutrition education (SNE) on sustainable eating behaviors and anthropometric measurements in women.
Design: In the research, a pretest-posttest quasi-experimental design was used for groups that were subjected to two different trainings.
Sample: In the education group, 34 and in the control group, 51 women that between the ages of 19-50 years from six Women's Education and Culture Centers of Ankara Altındağ Municipality.
Article Synopsis
- Richter's Transformation (RT) is a dangerous progression of chronic lymphocytic leukemia (CLL) that appears as diffuse large B-cell lymphoma, with a key role suspected for protein arginine methyltransferase 5 (PRMT5).
- Research shows that PRMT5 is consistently overexpressed in patients developing RT and that mice with increased levels of PRMT5 face a higher death risk and develop aggressive B-cell diseases similar to RT.
- The study also introduces PRT382, a new and selective inhibitor of PRMT5, suggesting its potential for targeted treatment in aggressive cases of CLL and RT, highlighting the need for clinical trials.
Chronic lymphocytic leukemia (CLL) is a quiescent B-cell malignancy that depends on transcriptional dysregulation for survival. The histone deacetylases are transcriptional regulators whose role within the regulatory chromatin and consequence on the CLL transcriptome is poorly characterized. Here, we profiled and integrated the genome-wide occupancy of HDAC1, BRD4, H3K27Ac, and H3K9Ac signals with chromatin accessibility, Pol2 occupancy, and target expression signatures in CLL cells.
View Article and Find Full Text PDFN-methyladenosine (mA), the most abundant internal modifier of mRNAs installed by the methyltransferase 13 (METTL3) at the (G/A)(mA)C motif, plays a critical role in the regulation of gene expression. METTL3 is essential for embryonic development, and its dysregulation is linked to various diseases. However, the role of METTL3 in liver biology is largely unknown.
View Article and Find Full Text PDFEpithelial growth factor-like 7 (EGFL7) is a protein that is secreted by endothelial cells and plays an important role in angiogenesis. Although EGFL7 is aberrantly overexpressed in solid tumors, its role in leukemia has not been evaluated. Here, we report that levels of both mRNA and EGFL7 protein are increased in blasts of patients with acute myeloid leukemia (AML) compared with normal bone marrow cells.
View Article and Find Full Text PDF