The relationship of periodontal disease severity to serum and GCF substance P levels in diabetics.

Objective: To compare circulating and gingival crevicular fluid (GCF) substance P concentrations in well- and poorly controlled type 2 diabetic patients with chronic periodontitis.

Method And Materials: Forty-five serum and 90 GCF samples were collected from diabetic patients with periodontal disease, and the concentrations of substance P were quantified by radioimmunoassay.

Results: Serum substance P levels were higher in the poorly controlled diabetic group than in patients with good glycemic control (P = .

Amelogenesis imperfecta, hypoplastic type associated with some dental abnormalities: a case report.

Amelogenesis imperfecta (AI) is a hereditary disorder expressing a group of conditions that cause developmental alterations in the structure of enamel. AI is a serious problem that reduces oral health-related quality of life and causes some physiological problems. The treatment of patients with AI may upgrade the quality of life and reinforce their self-esteem.

Local peptidergic innervation of gingiva in smoking and non-smoking periodontitis patients.

Background: The present study aimed to investigate the local peptidergic innervation of diseased and healthy periodontia in smokers and non-smokers.

Methods: Fifteen smokers and 12 non-smokers, all with localized chronic periodontitis, participated in the study. Periodontally diseased and healthy tooth sites were selected in smokers (groups 1 and 2, respectively) and non-smokers (groups 3 and 4, respectively).