[The role of respiratory viruses in etiology of rhinosinisitis in the children].

The objective of the present study was to elucidate the role of respiratory viruses in etiology of acute rhinosinusitis (ARS) in the children and adolescents. We analysed the results of a microbiologial study of 50 aspirates from the paranasl sinuses. It was shown that acute rhinosinusitis had bacterial and viral-bacterial etiology in 8% and 24% of the cases respectively.

[The two-phase growth medium for sub-culturing of Helicobacter pylori].

A. Pylori is a very undemanding microorganism needing the in support of complex of conditions including particular atmosphere, temperature of culturing and composition of growth medium. The two-phase growth medium is recommended to sub-culturing in Petri dishes with diameter of 90 mm.

[Ergoferon and oseltamivir in treatment of influenza: results of multicentre randomized comparative clinical trial].

The narrow range of choice and virus resistance to the most common drugs require search and introduction of new drugs with proven efficacy and safety for the treatment of influenza. Ergoferon is a new combined medicine containing release active antibodies to interferon-gamma (anti-IFNgamma), CD4-coreceptor and histamine. The formulation influences various links of antiviral defense and provides antiinflammatory effect.

[Hepatitis E: current concepts].

Hepatitis E belongs to the group of enetral hepatites. Its earlier cases caused by genotype I and II viruses were reported largely from epidemics affecting tropical and subtropical countries. Sporadic cases of hepatitis E recorded later in West Europe, North America, Southeast Asia, and Oceania were caused by genotype III and IV viruses.

[Risks of infectious disease transmission during endoscopy].

In article the objective and subjective reasons are stated, not allowing to provide infectious safety of endoscopic procedures, offers on maintenance of system of infectious safety of endoscopic manipulations.

[Improvement of natural resistance in children for prophylaxis of influenza and acute respiratory tract viral infections (results of multicenter randomized trials)].

The results of the multicentre clinical trials on cycloferon efficacy in children at the age from 4 to 16 years are presented. The prophylactic effect of the drug (2.9-7.

[Characteristics of the immune status in specific and nonspecific prophylaxis of influenza in elderly persons].

The results of the comparative analysis of the immunological effectiveness of the anti-influenza vaccine Vaxigrip, the inferferon inductor Arbidol and their combination in 125 elderly persons are presented. In the process of investigations the immunomodulating activity of the preparations under study was noted; this activity was manifested by the increase of the absolute and relative number of cells, carrying markers CD3+, CD4+ and CD16+, but not CD8+, CD19+ and CD25+, the normalization of the immunoregulatory index and the stimulation of the phagocytic function in the absence of essential influence on the level of HLA-DR+ expression and the concentration of immunoglobulins of the main classes. An increase in the frequency of seroconversions and the multiplicity of growth in the titers of specific antibodies to influenza viruses A (H1N1 and H3N2) and B, most pronounced in persons immunized with the vaccine simulianeouslywith the injection of Arbidol, was established.

[Cycloferon--a new domestic preparation for the prophylaxis of influenza and other acute respiratory viral infections].

The results of the placebo-controlled multicenter study of the epidemiological efficiency of the preparation Cycloferon for the prophylaxis of acute respiratory viral infections in children and adolescents are presented. A total of 16,000 children and adolescents were selected for the study. The epidemiological efficiency of the preparation manifested in 1.

[Specific prophylaxis of influenza with inactivated split vaccine Vaxigrip].

Influenza remains a serious health problem, annually causing epidemics embracing up to 10% of the population of the world, and at the periods of pandemics this number may rise 4- to 6-fold. In the overwhelming majority of the countries the prophylaxis of influenza is carried out at present out with the use of inactivated vaccines. One of such vaccines is the highly purified split vaccine Vaxigrip (Aventis-Pasteur, France), permitted for use in Russia since 1992.

[Circulation of respiratory viruses in Moscow and their role in acute respiratory diseases morbidity].

Statistical data obtained during prolonged investigations on the structure of infective agents isolated from patients with acute respiratory diseases (ARD) in Moscow in 1989-1999 were analyzed. The study revealed that fluctuations of ARD morbidity rates were linked with the prevailing circulation of one or another type of the virus. The absence of the dominating role of influenza viruses was confirmed.

[Effect of amyxin--a domestic analog of tilorone--on characteristics of interferon and immune status of man].

The influence of amyxin, the Russian oral analog of tilorone, on the human interferon and immune status has been evaluated. As revealed by this investigation the administration of amyxin has produced a rise in the content of serum interferon, an increase in the capacity of leukocytes and lymphocytes for synthesizing alpha- and gamma-interferon, the activation of NK and phagocytizing cells of peripheral blood. No essential influence of amyxin on the amount of B and T lymphocytes, their subpopulations and the levels of the main classes of immunoglobulins has been established.

[Evaluation of amyxin effect in prophylaxis of acute respiratory viral infections].

The results of the evaluation of the oral inductor of endogenic interferon (amyxin), manufactured in Russia are presented. The use of amyxin was found to produce a drop in morbidity in acute respiratory virus infections (ARVI) among medical workers 3.4 times, i.

[Distribution and features of infection with hepatitis viruses B and C during hemodialysis treatment].

The prevalence of hepatitides B and C was evaluated in 140 patients treated by hemodialysis. Almost half of patients (48%) had acute hepatitis B which completely resolved. Acute hepatitis B was detected in 6% in the course of observation.