Publications by authors named "Sekhar P Chandra"

Article Synopsis
  • The study explores the COVIDSeq protocol for efficient diagnosis and genetic analysis of SARS-CoV-2, highlighting its effectiveness in handling high-throughput testing during the COVID-19 pandemic.
  • Results show that COVIDSeq has a high concordance with traditional RT-PCR tests and even identified cases that were missed by RT-PCR, emphasizing its viability as a confirmatory testing method.
  • The research also contributes to the understanding of the genetic diversity of SARS-CoV-2, reporting new lineages and a high number of unique genetic variants for the first time in India.
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A new series of lanthanum(iii) complexes was synthesized using a -anisidine-appended 1-hydroxy-2-acetonapthanone (3) Schiff base and characterized spectroscopic methods. The ligand was synthesized sonication and the crystalline product was characterized using X-ray crystallography. The genotoxicity of the compound was assessed primarily by the bacterial reverse mutation (Ames) test and the mammalian chromosome aberration test; in both cases, the samarium complex 5 was found to be non-mutagenic.

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Objective: The diverse subset of oral squamous cell carcinoma (OSCC) with different clinical appearance and outcome, independent of traditional risk factors has led to increasing attention in human papillomavirus (HPV) infection.

Materials And Methods: The investigation followed a case-control design. Information pertaining to the subjects was retrieved from hospital records.

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This clinical study was to demonstrate the applicability of diffuse reflectance (DR) intensity ratio R620/R575 in the quantification and discrimination of periodontitis and gingivitis from healthy gingiva. DR spectral measurements were carried out with white-light illumination from 70 healthy sites in 30 healthy volunteers, and 63 gingivitis- and 58 periodontitis-infected sites in 60 patients. Clinical parameters such as probing pocket depth, clinical attachment level, and gingival index were recorded in patient population.

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Osteod osteoma, although not a common clinical occurrence, does pose problems both in diagnosis and surgical management. Initial plain radiographic diagnosis is sometimes fraught with the limitation of not being able to differentiate from chronic osteomyelitis and stress fracture. CT-aided localization of the nidus is also often inconclusive.

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