Biocompatibility Evaluation of Ampicillin-Loaded Whitlockite for Bone Regeneration.

Introduction Whitlockite (WH), a rare phosphate mineral within the apatite group, shows potential for bone regeneration owing to its superior composition and biocompatibility compared to hydroxyapatite. It can serve as a carrier for bioactive molecules, gradually releasing them to stimulate bone growth and expedite healing. This study aims to assess the biocompatibility of antibiotic-loaded WH, focusing on ampicillin, for bone regeneration applications.

Analyzing the Surface Topography of Hafnium Nitride Coating on Titanium Screws: An In Vitro Analysis.

Background The use of surface coatings to enhance the properties lacking in titanium has attracted significant focus in recent times. Hafnium nitride (HfN) coatings could be explored as promising in the osteoinductive properties of titanium implants. HfN exhibits excellent mechanical attributes, such as hardness and wear resistance, and is often used as a coating on high-end equipment for protection.

Evaluation of Corrosive Properties of Hafnium Nitride Coating Over Titanium Screws: An In Vitro Study.

Background Varied surface coatings have been studied time and again in medical sciences. Whether general or dental, studying the performance of coatings aims to assess their potential to improve the durability and longevity of titanium implants, thereby advancing implant technology for enhanced patient outcomes. Various analytical techniques are utilized to assess the performance of the coating, providing insights into its effectiveness in preventing corrosion.

In Vitro Biocompatibility Assessment of a Novel Membrane Containing Magnesium-Chitosan/Carboxymethyl Cellulose and Alginate Intended for Bone Tissue Regeneration.

Bone tissue engineering (BTE) is an emerging interdisciplinary field that aims to develop new strategies and materials for repairing, regenerating, or replacing damaged bone tissues. This field combines engineering, biology, and medicine principles to create functional bone tissues in the laboratory and in vivo. The main goal of BTE is to create biological substitutes that mimic the structure, function, and properties of natural bone tissue, thereby promoting the regeneration of bone defects caused by trauma, disease, or aging.

Osteogenic and Biomedical Prospects of Hafnium and Its Compounds: A Scoping Review.

The direct engagement of hafnium (Hf) in biological processes or its critical function in living things is not well understood as of now. Unlike key elements like oxygen, carbon, hydrogen, and nitrogen, which are necessary for life, Hf is not known to have any biological activities or functions. It is essential to acknowledge that scientific research is ongoing and that new findings may have been made.

Type 1 collagen: Synthesis, structure and key functions in bone mineralization.

Collagen is a highly abundant protein in the extracellular matrix of humans and mammals, and it plays a critical role in maintaining the body's structural integrity. Type I collagen is the most prevalent collagen type and is essential for the structural integrity of various tissues. It is present in nearly all connective tissues and is the main constituent of the interstitial matrix.

Chitosan derived chito-oligosaccharides promote osteoblast differentiation and offer anti-osteoporotic potential: Molecular and morphological evidence from a zebrafish model.

This study delves into the potential of chito-oligosaccharides (COS) to promote osteoblast differentiation and prevent osteoporosis, utilizing experiments with mouse MSCs and the zebrafish model. The preliminary biocompatibility study affirms the non-toxic nature of COS across various concentrations. In the osteoblast differentiation study, COS enhances ALP activity and calcium deposition at the cellular level.

Zinc and Silver-Infused Calcium Silicate Cement: Unveiling Physicochemical Properties and In Vitro Biocompatibility.

Introduction: Calcium silicate-based types of cement have gained recognition in various dental applications due to their exceptional sealing capabilities, bioactivity, and minimal adaptability. However, these materials have certain shortcomings that can lead to mechanical failures and premature degradation. The inclusion of metal ions into their structure is expected to promote their biological activity.

An Invitro Chewing Simulation Study Comparing the Wear Resistance Behavior of Polyetheretherketone-Layered Composite Crown and Ceramic-Layered Zirconia Crown.

Objective: This study aimed to compare the wear resistance and color stability of fixed dental prostheses (FDPs) fabricated using two different materials: zirconia veneered with feldspathic porcelain and polyetheretherketone (PEEK) veneered with indirect composite. The assessment included samples subjected to thermocycling and wear simulation.

Methods: Two groups of FDPs were examined: one made of zirconia veneered with feldspathic porcelain (control and thermocycled) and the other made of PEEK veneered with indirect composite (worn and thermocycled).

miRNA Associated With Glucose Transporters in Oral Squamous Cell Carcinoma: A Systematic Review.

Oral squamous cell carcinoma (OSCC) is a malignancy of the oral cavity with poor prognosis. Dysregulation in glycolytic pathways involving glucose transporters (GLUT) has been implicated in poor prognosis. Furthermore, GLUT expression in cancer cells is regulated by several miRNAs.

Digital Panoramic Radiographs for Age Prediction Utilizing the Tooth Coronal Index of First Mandibular Bicuspids Among the South Indian Population.

Introduction Age estimation holds significant importance within the realm of forensic science, serving as a crucial tool for various purposes such as validating birth certificates, aiding immigration processes, and determining eligibility for retirement benefits. Additionally, age estimation carries significant implications in situations involving human trafficking, offering insights into matters such as legal culpability, adult classification, and marriage age assessment. Aim The purpose of this research was to assess the precision of the Tooth Coronal Index (TCI) in the estimation of age, a key component of forensic odontology.