- The nucleolus is a part of a cell's nucleus and helps in making ribosomes, which are important for making proteins.
- Scientists found that the nucleolus can form through a process called liquid-liquid phase separation (LLPS), where certain proteins and RNA come together, but interestingly, this formation doesn't depend on a specific type of RNA.
- In new research, it was discovered that a ribosomal protein called uL30 and a key nucleolar protein known as nucleophosmin (NPM) can create droplets without RNA, and that reducing uL30 levels in cells decreases the number of nucleoli.