The target site of the novel fungicide quinofumelin, class II dihydroorotate dehydrogenase.

The target site of the novel fungicide quinofumelin was investigated in the rice blast fungus . Quinofumelin-induced mycelial growth inhibition was reversed by orotate but not by dihydroorotate. Recovery tests suggested that the target site of quinofumelin was dihydroorotate dehydrogenase (DHODH), which catalyzes the oxidation of dihydroorotate to orotate.

Effects of liquid konjac on parameters related to obesity in diet-induced obese mice.

Konjac-mannan has been suggested to exert a protective effect against visceral obesity. However, there is little knowledge about the effects of liquid konjac (LK) that is partially alkali gelled. The purpose of the present work was to evaluate the potential beneficial effects of a LK powder on obesity in mice.