Mastoid obliteration combined with soft-wall reconstruction of posterior ear canal.

To clarify the usefulness of modified soft-wall reconstruction method by combing with mastoid obliteration, 96 patients (98 ears) with their age ranging from 5 to 82 (average 51.3), including 62 ears with chronic otitis media (COM) with cholesteatoma, 18 ears with non-cholesteatomatous COM, 14 ears with postoperative cavity problem, and 4 ears with adhesive-type COM, who had soft-wall reconstruction of the posterior ear canal and mastoid obliteration using mainly bone powder following mastoidectomy, were evaluated their postoperative conditions more than a year after surgery. Overall success rate was 76.

Clinical efficacy of 5-fluorouracil (5-FU) topical cream for treatment of cholesteatoma.

Objective: In order to clarify clinical efficacy of commercially available 5-fluorouracil (5-FU) topical cream, a clinical study was conducted.

Methods: Two to three cubic millimetres of 5-FU topical cream (Kyowa, Roche) was applied on 50 cases of various types of cholesteatoma (50 patients) two to five times with the interval of 2 weeks, and its clinical efficacy was evaluated by the criteria we developed.

Results: In total, 59% of the cholesteatomas showed good effect, 29% of them showed fair effect, and the effect was poor in the remaining 12%.

Postnatal change on the location of Ostmann's fatty tissue in the region lateral to Eustachian tube.

Objective: To delineate a possible role of protective function by Ostmann's fatty tissue (OF) in the lateral region to Eustachian tube (ET).

Study Design: Morphometric and histopathological examination on human temporal bones.

Methods: OF in the region lateral to the cartilaginous portion of the ET between the ET lumen and the tensor veli palatini muscle (TVP) was studied histopathologically and morphometrically by analyzing a series of vertically cut histologic sections for the ET structures.

Postnatal changes in the connective tissue in the region lateral to the eustachian tube: possible relationship to tube function.

In order to delineate the possible role of connective tissue (CT) in the region lateral to the eustachian tube (ET) between the ET lumen and the tensor veli palatini muscle (TVPM), we studied the postnatal changes in the CT in histologic sections of human ET. In fetuses and neonates, the lateral region was filled with mesenchyme. Loose collagenous CT appeared first at 2 weeks of age, and in subjects older than 4 years of age, the collagen formed dense, meshlike structures attaching to both the subepithelial CT layer of the ET and the tendonlike membrane of the TVPM.

Proximity of carotid canal wall to tympanic membrane: a human temporal bone study.

Objective: The objective was to examine the possible risk of injury to the internal carotid artery during procedures in the middle ear, including myringotomy.

Study Design: Histopathological morphometric study of human temporal bones.

Methods: One hundred forty-two human temporal bone specimens obtained from 92 individuals without any known ear disease were prepared for light microscopic study.

Postnatal development of the eustachian tube glands.

Objective: To delineate a possible difference in the function of the eustachian tube (ET) between infants and adults.

Study Design: Morphometric and histopathological examination on the human temporal bones.

Methods: The secretory glands in the ET were studied in serial histological sections through the cartilaginous portion of the human ET obtained from 32 individuals whose ages ranged from 1 day to 19 years.

Cerebellar arteriovenous malformation with facial paralysis, hearing loss, and tinnitus: a case report.

Objective: To describe cerebellar arteriovenous malformation in a 21-year-old man with symptoms resembling those of ear disease and to discuss the relationship between the findings of neurotologic examination and magnetic resonance imaging.

Study Design: Case report.

Setting: Department of Otolaryngology, Head-and-Neck Surgery of the Kyoto University Hospital, which is a tertiary care center, in Kyoto, Japan.