Verification of a Motion Sensor for Evaluating Physical Activity in COPD Patients.

Background: Objective evaluation of the physical activity (PA) in patients with chronic obstructive pulmonary disease (COPD) is important. We validated a triaxial accelerometer, Active Style Pro HJA-750C® (HJA), and evaluated the necessary conditions for obtaining reproducible data.

Methods: The PA measured by HJA was compared with that measured by two already validated accelerometers in 11 patients with COPD (age: 76.

Spectral evidence and DFT calculations on the formation of Bis(2,2'-bipyridine)platinum(II)-N-base adducts.

The formation of 1:1 adducts of Pt(bpy)2(2+) (bpy = 2,2'-bipyridine) with various N bases (B) has been ascertained in water at ambient temperature by spectrophotometric titration and electrospray ionization mass spectroscopy. A pseudo-five-coordinated complex, [Pt(bpy)2(B)](2+) with a monodentating bpy, is proposed based on density functional theory calculation. The formation constants (Kc) increase with the nucleophilicity of B except for sterically hindered N-bases, indicating an associative ligand-substitution mechanism.