Publications by authors named "Seijiro Sonoda"

Background: A patient with undiagnosed tracheomalacia undergoing surgery experienced accidental expiratory central airway collapse after tracheal intubation. Here, we aimed to diagnose tracheomalacia from the preoperative data.

Case Presentation: A 73-year-old man, scheduled for abdominal surgery, had a clinical history of chronic obstructive pulmonary disease.

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Case: A 20-year-old woman developed acute psychotic symptoms and altered level of consciousness. She presented with neck stiffness, tremulous arms, facial dyskinesia, and distension of the lower abdomen. Pelvic magnetic resonance imaging showed bilateral ovarian teratomas.

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A 44-year-old man underwent radical thymectomy for malignant thymoma 5 years ago. He subsequently underwent right extrapleural pneumonectomy because a right pleural metastatic lesion had developed. The operation was completed uneventfully.

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A 35-year-old primigravida with twin gestation was admitted for elective cesarean section. She had no preoperative systemic diseases including heart disease. At 37 weeks of gestation, elective cesarean section was performed under combined spinal-epidural anesthesia.

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It is unclear whether nitrous oxide (N(2)O) has a protective effect on cardiac function in vitro. In addition, little is known about the cardioprotective effect of anesthesia administered during hypoxia or ischemia. We therefore studied the cardioprotective effects of N(2)O and sevoflurane administered before or during hypoxia in isolated rat hearts.

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Background: We compared the effects of nitrous oxide (N2O) plus isoflurane with equianesthetic isoflurane alone on the L-type calcium current (I(Ca,L)), and also investigated their modulation of beta-adrenoceptor stimulation.

Methods: I(Ca,L) was recorded from enzymatically isolated rabbit ventricular myocytes using the whole-cell patch clamp technique. Ventricular myocytes were exposed to prepluses of -40 mV from a holding potential of -80 mV and then to +50 mV in 10 mV increments and thereafter the depolarization pulses that acquire peak currents were applied every 10 seconds.

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