Publications by authors named "Seiedhadi Saghaleini"

Introduction: Pro-inflammatory responses have an important role in developing coronavirus disease 2019 (COVID-19). L-carnitine (LC) has been known to possess anti-inflammatory, anticoagulant, and antiviral effects. So, we aimed to evaluate the efficacy of LC in hospitalized patients with moderate-to-severe COVID-19.

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Article Synopsis
  • Ventilator-associated events (VAEs) are a major concern in critically ill patients, prompting a study to compare closed and open endotracheal suctioning systems in preventing ventilator-associated pneumonia (VAP).
  • A literature review identified 10 eligible randomized controlled trials, revealing that open suction systems significantly increased VAP incidence by 57% compared to closed systems.
  • While closed suction systems show promise in reducing VAP, further research with larger sample sizes is needed before making them the standard choice for all patients, considering individual circumstances and costs.
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