Publications by authors named "Seidov V"

The purpose of the study was to compare long-term results of angioplasty and coronary arterial stenting (CAS) depending on the initial degree of coronary arterial (CA) lesion according to morphological stenosis classification, as well as to evaluate the influence of re-stenosis on myocardial contractility dynamics, anginal recurrence rate, and exercise tolerance. The subjects, 228 men after angioplasty and 184 men after CAS with wire stents without drug coating, were included in the study between 1989 and 2005. Coronarography was repeated in 358 patients one year after surgery.

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In 6 patients with uncomplicated gastric ulcer (GU) and 8 patients with GU complicated by acute bleeding morphohistochemical and ultrastructural analysis of apudocytes of gastric mucous membrane in the ulcer, periulcer and remote zone was carried out with detection of morphofunctional changes predicting ulcer bleeding. It is established that G- and ECL-apudocytes hyperplasia and hyperfunction in these zones have stable, irreversible nature in gastric ulcer bleeding, and are reliable prognostic criteria of this complication.

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In 24 patients with uncomplicated duodenal ulcer and 40 patients with acute bleeding duodenal ulcer morphofunctional status of the local paraendocrine adjusting system of the duodenal mucous membrane in the periulcer, ulcer and remote zones was studied with histochemical and electron-microscopic techniques. It is established, that ECL- and G-apudocytes hyperplasia and hyperfunction and vice versa D-cells reduction of the number and suppression of the secretory activity are reliable prognostic criteria of duodenal ulcer bleeding.

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Two methods of resection of the stomach by Billroth II were developed with creation of transversal termino-lateral gastroenteroanastomosis (TTLGEA) and transversal latero-lateral gastroenteroanastomosis (TLLGEA) using compression implant from nickel-titan alloy which possessed "memory of the form" (IMF). 231 resections of the stomach by Billroth II were carried out with formation TTLGEA in 181 cases and TLLGEA in 50 cases. Complications after these operations with compression gastroenteroanastomosis were studied as well as endoscopic and roentgenologic picture of the anastomosis in early postoperative period.

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The authors analyse the causes of 170 (38.3%) complications which occurred after 435 interventions for selective proximal vagotomy (SPV) with or without a stomach-draining operation. Specific complications were encountered in 31.

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Under analysis were results of observations of 112 patients after Billroth-II resection with different modifications who suffered of disorders of the duodenal patency before operation. A conclusion is made of the necessity of a complex preoperative examination of the patients in order to reveal chronic disorders of the duodenal patency as well as of the expediency of using operations correcting the disorders of the duodenal patency--dissection of the Treitz ligament, duodenojejunostomy simultaneously with Billroth-II resection of the stomach.

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From study of the condition of the upper gastrointestinal tract in 51 patients suffering from the dumping syndrome after Hofmeister-Finsterer modification of Billroth II gastrectomy, the authors concluded that the intracavitary pressure gradient between the gastric stump and the efferent intestinal loop, as well as the diameter of the gastroenteroanastomosis, influence the dumping syndrome. A method is suggested for measuring the diameter and surface of the gastroenteroanastomosis and measuring the intracavitary pressure in the Gastric and duodenal stump and the efferent and afferent loops of the small intestine.

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Selective proximal vagotomy (SPV) was performed in 435 patients whose age ranged from 16 to 80. The isolated variant of SPV was applied in 130 and SPV with a stomach draining operation was conducted in 305 patients; 320 patients were examined after the operation in follow-up periods of 7 years and more. Postoperative lethality was 0.

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To study the effect of abdominal aorta clamping and revascularization and appraise the efficacy of the drug gordox during surgical intervention, the values of the kinin system, acid-base balance, acid metabolites, and the total activity of lactic dehydrogenase and its isoenzymatic spectrum were determined in 24 patients with aortic stenosis of atherosclerotic origin. In patients who did not receive gordox, the kinin system became markedly activated after the clamp was removed from the aorta, which led to a sharp fall in arterial pressure, the development of metabolic acidosis, and activation of enzymes of the glycolytic cycle. Preventive administration of gordox in the other group of patients during operation inhibited the processes of activation of the kinin system, stabilized hemodynamics, improved tissue circulation and prevented the development of hypoxia.

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