Immunohistochemical Differentiation between Western and East Asian Types of CagA-Positive in Gastric Biopsy Samples.

Background: Cag A-positive isolated from human gastric mucosa is categorized as a Western or East Asian allele-type based on whether the gene encodes an EPIYA-C or EPIYA-D motif. We aimed to differentiate between the 2 types of by immunohistochemistry (IHC) using formalin-fixed paraffin-embedded (FFPE) gastric biopsy samples.

Materials And Methods: We developed 2 monoclonal antibodies (mAbs) that detect either the EPIYA-C or EPIYA-D motif of the CagA protein by IHC using FFPE tissues.

Colonic Pseudolipomatosis: A Rare but Characteristic Endoscopic Condition.

BACKGROUND Colonic pseudolipomatosis (CP) can pose a diagnostic challenge due to its rare incidence and multiple presentations, most of them not very familiar to the endoscopist. Its etiology and pathogenesis have not been completely clarified. It can be related to mucosal iatrogenic injury caused during endoscopic examination or to chemical injury caused by residual disinfectants on the surface of the scope after cleansing.

Measurement of middle ear transfer function in temporal bones using electromagnetic excitation: Comparison to sound excitation and evaluation of influencing factors.

Hearing a sound produces vibrations of the ossicles in the middle ear, which can be measured in the micrometer to nanometer range. Destruction of middle ear structures results most commonly from chronic inflammatory diseases. In these cases, passive and active middle ear implants are used for reconstruction of the ossicular chain.

Differences in Pathology and Mutation Status Among Colorectal Cancer Patients Younger Than, Older Than, and of Screening Age.

Background: Screening protocols for colorectal cancer are broadly recommended and effective in reducing mortality. However, populations from different age groups can harbor distinct pathologic and molecular profiles that can also be influenced by screening and polyp resection, especially in older ages.

Patients And Methods: We retrospectively analyzed tumors from stage IV colorectal cancer patients from a central pathology laboratory in Brazil that is a reference for mutational profiling countrywide.

[Active hearing implants in chronic otitis media].

In patients with inadequate hearing improvement after tympanoplasty and failure of conventional hearing aid fitting, active hearing implants provide an alternative treatment option. Active middle ear implants function as a vibromechanical bypass of the stiffness and damping effect of a poorly oscillating tympanic membrane and the (reconstructed) ossicular chain. The selection of the hearing system depends on the maximum output levels of the hearing system and the anatomical conditions in mostly multiply operated ears.

Implementation and Long-Term Evaluation of a Hearing Aid Supported Tinnitus Treatment Using Notched Environmental Sounds.

Recent work has shown that sharp spectral edges in acoustic stimuli might have advantageous effects in the treatment of tonal tinnitus. In the course of this paper, we evaluate the long-term effects of spectrally notched hearing aids on the subjective tinnitus distress. By merging recent experimental work with a computational tinnitus model, we modified the commercially available behind-the-ear hearing aids so that a frequency band of 0.

Free-field evoked auditory brainstem responses in cochlear implant users.

The importance of binaural cues in auditory stream formation and sound source segregation is widely accepted. When treating one ear with a cochlear implant (CI) the peripheral auditory system gets partially replaced and processing delays get added potentially, thus important interaural time differences get altered. However, these effects are not fully understood, leaving a lack of systematic binaural fitting strategies with respect to an optimal binaural fusion.

IVTH BRAZILIAN CONSENSUS CONFERENCE ON HELICOBACTER PYLORI INFECTION.

Significant progress has been obtained since the III Brazilian Consensus Conference on H. pylori infection held in 2012, in Bento Gonçalves, Brazil, and justify a fourth meeting to establish updated guidelines on the current management of H. pylori infection.

Neurodynamic evaluation of hearing aid features using EEG correlates of listening effort.

In this study, we propose a novel estimate of listening effort using electroencephalographic data. This method is a translation of our past findings, gained from the evoked electroencephalographic activity, to the oscillatory EEG activity. To test this technique, electroencephalographic data from experienced hearing aid users with moderate hearing loss were recorded, wearing hearing aids.

MARRIAGE GAP IN CHRISTIANS AND MUSLIMS.

For modern Western societies with a regime of monogamy, it has recently been demonstrated that the socioeconomic status of men is positively associated with being or having been married. This study aims to compare marriage patterns (if a person has been married at least once) for cultures with a tradition of monogamy and polygyny. As no worldwide data on polygyny exist, religion was used as a proxy for monogamy (Christians) vs polygyny (Muslims).

Detection of binaural interaction in free-field evoked auditory brainstem responses by time-scale representations.

The so called β-wave of the binaural interaction component (BIC) in auditory brainstem responses (ABR) has been shown to be an objective measure for binaural interaction (BI). This component is the arithmetical difference between the sum of the monaurally evoked ABRs and the binaurally evoked ABR. Unfortunately, these neural responses are known to be very fragile and as a result the calculated BIC.

A multidisciplinary systematic review of the treatment for chronic idiopathic tinnitus.

The majority of tinnitus patients are affected by chronic idiopathic tinnitus, and almost 60 different treatment modalities have been reported. The present study is a multidisciplinary systematic analysis of the evidence for the different forms of treatment for chronic tinnitus. The results are used to form the basis of an S3 guideline.

Evaluation of an objective listening effort measure in a selective, multi-speaker listening task using different hearing aid settings.

Speaker recognition in a multi-speaker environment is a complex listening task that requires effort to be solved. Especially people with hearing loss show an increased listening effort in demanding listening situations compared to normal hearing people. However, a standardized method to quantify listening effort does not exist yet.

Dysfunctional long term habituation to exogeneous tinnitus-matched sounds in patients with high tinnitus distress.

During the last years, the demand of accurate diagnostic tools for individualized tinnitus treatment gradually increased. Today several different psychometric instruments for the estimation of the patients degree of decompensation with clinical relevance have emerged. All of these tools are questionnaires for a subjective self-assessment and have deficits in comparability due to severe differences in their factor structure in the anamnesis.

Inconsistent year-to-year fluctuations limit the conclusiveness of global higher education rankings for university management.

Backround. University rankings are getting very high international media attention, this holds particularly true for the Times Higher Education Ranking (THE) and the Shanghai Jiao Tong University's Academic Ranking of World Universities Ranking (ARWU). We therefore aimed to investigate how reliable the rankings are, especially for universities with lower ranking positions, that often show inconclusive year-to-year fluctuations in their rank, and if these rankings are thus a suitable basis for management purposes.

[Listening effort with cochlear implants: Unilateral versus bilateral use].

Aim: The influence of bilateral cochlear implants (CI) and unilateral CI on the self-reported listening effort in standardized situations is being assessed.

Sample And Methods: The sample consisted of 34 bilateral and 38 unilateral adult CI users. Unilateral CI users had at least severe hearing loss in the non-implanted ear and had been fitted with a hearing aid.

[On the interdisciplinary S3 guidelines for the treatment of chronic idiopathic tinnitus].

Introduction: Tinnitus is a frequent symptom, which, particularly in combination with comorbidities, can result in a severe disease-related burden. Chronic idiopathic tinnitus (CIT) is the most frequent type of tinnitus. A considerable number of treatment strategies are used to treat CIT-for many of which there is no evidence of efficacy.

A combined morphometric analysis of foot form and its association with sex, stature, and body mass.

Objectives: Morphometric analysis of footprints is a classic means for orthopedic diagnosis. In forensics and physical anthropology, it is commonly used for the estimation of stature and body mass. We studied individual variation and sexual dimorphism of foot dimensions and footprint shape by a combination of classic foot measurements and geometric morphometric methods.

Objective assessment of listening effort in the oscillatory EEG: comparison of different hearing aid configurations.

An objective estimate of listening effort could support the hearing aid fitting procedure. Most of the digital hearing aids have already hearing aid settings which are supposed to reduce the listening effort, but the effects of these settings on the individual's listening effort remain unclear. In this study, we propose an objective estimate of listening effort using electroencephalographic data.

IMP3 expression in gastric cancer: association with clinicopathological features and HER2 status.

Background: The aim of this study was to evaluate the expression of IMP3, an independent poor prognostic factor for many cancers, and its association with clinicopathological features and HER2 status.

Methods: Gastrectomy specimens from 106 patients were evaluated by immunohistochemistry and fluorescence in situ hybridization.

Results: HER2 overexpression was found in 4.

Geometric morphometric footprint analysis of young women.

Background: Most published attempts to quantify footprint shape are based on a small number of measurements. We applied geometric morphometric methods to study shape variation of the complete footprint outline in a sample of 83 adult women.

Methods: The outline of the footprint, including the toes, was represented by a comprehensive set of 85 landmarks and semilandmarks.

Ownership of dwelling affects the sex ratio at birth in Uganda.

Background: Socio-economic conditions can affect the secondary sex ratio in humans. Mothers under good environmental conditions are predicted to increase the birth rates of sons according to the Trivers-Willard hypothesis (TWH). This study analyzed the effects of ownership and non-ownership of dwellings on the sex ratio at birth (SRB) on a Ugandan sample.