Publications by authors named "Sehyun Han"

The aim of this study was to determine the effects of traffic-related particulate matter (PM) on allergic inflammation of ocular surfaces. BALB/c mice were sensitized with ovalbumin (OVA) and aluminum hydroxide via intraperitoneal injection. Two weeks later, mice were challenged with eye drops containing OVA concomitant with either traffic-related PM or vehicle eye drops.

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In this study, we examined tire and road wear microparticles (TRWMPs) in road dust along the Seoul metropolitan area, from industrial and residential areas. The road dust samples were collected via vacuum sweep methods and then filtered to obtain particles with diameters less than 75 μm. To quantify the TRWMPs in road dust, we used the raw materials of tire components, natural rubber (NR), and styrene-butadiene rubber (SBR), as standard materials.

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Air pollution caused by particulate matter (PM) has become a serious issue, and significant research has focused on managing large stationary emission sources, i.e., the primary sources of PM.

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Ambient particulate matter (PM), a major component of air pollution, aggravates ocular discomfort and inflammation, similarly to dry eye disease (DED) or allergies. However, the mechanism(s) by which PM induces the ocular inflammatory response is unknown. This study investigated the immunological response of traffic-related fine particulate matter (PM) on the ocular surface in a murine model.

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Article Synopsis
  • * The nanoparticles displayed a bimodal size distribution, with significant peaks between 70-100 nm and 10-20 nm, and the concentration of smaller particles (10 nm) increased significantly with more printer operation.
  • * A prediction model showed that many nanoparticles (10-30 nm) could be deposited in the lower human respiratory tract, and 14 different HAPs were found, with hexane, acrylonitrile, and benzene being the most prevalent.
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Most studies on the adverse effects of air pollution have focused on respiratory and cardiovascular diseases, and there are relatively few studies on eye diseases following exposure of ambient particulate matter (PM). Epidemiological and clinical researches correlating the eye and PMs have recently received attention. PMs are complex mixture of particles that vary in chemical composition and size.

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This study is considered the first attempt to apply a mobile monitoring system to estimating silt loading on paved roads in a megacity such as the Seoul metropolitan area. Using a mobile monitoring system developed in 2005, we estimated silt loadings on representative paved roads in the Seoul metropolitan area, including the city of Incheon, over a period of 3 yr. The temporal and spatial characteristics of silt loading were investigated for the carefully selected roads that may reflect the characteristics of the cities of Seoul and Incheon.

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