Publications by authors named "Segolene Lebrun"
J Antimicrob Chemother
July 2013
Article Synopsis
- The study aimed to explore how sub-MICs of antistaphylococcal antibiotics affect virulence factor expression in CA-MRSA strains.
- Clindamycin and linezolid were found to significantly lower the mRNA levels of Panton-Valentine leucocidin (PVL) and protein A (SpA), while tigecycline had a moderate effect, and daptomycin and vancomycin showed minimal impact.
- Overall, antibiotic type influenced the suppression of virulence factors, with clindamycin demonstrating the strongest and most consistent inhibitory effects across various strains.
