Rates of Vaccination against COVID-19 in Psychiatric Outpatients.

Background: The aim of this study was to compare the rates of vaccination against COVID-19 infection in psychiatric outpatients and the general population, as well as rates of infected patients. In addition, the level and type of anxiety due to the pandemic were observed in patients with psychotic, anxiety, and depressive disorders.

Materials And Methods: In the present study, 171 patients with pre-existing mental disorders completed the questionnaire about the doses and types of vaccination against COVID-19.

FAMILIAL CIRCUMSTANCES AND PSYCHOLOGICAL CHALLENGES IN ADOLOSCENTS WITH HISTORY OF CHILDHOOD ABUSE.

Violence, child abuse and neglect, which can lead to physical, psychological and social impairment and cause serious long-term consequences, are widespread throughout the world. The aim of our study is to examine the characteristics of the family and the emotional-behavioral difficulties of adolescents who were abused in childhood, compared with those who did not experience abuse. Sixty participants of both genders aged 12 to 18 years were divided into two groups (abused adolescents and the control group).

Implementation strategies for systematic conservation planning.

The field of systematic conservation planning has grown substantially, with hundreds of publications in the peer-reviewed literature and numerous applications to regional conservation planning globally. However, the extent to which systematic conservation plans have influenced management is unclear. This paper analyses factors that facilitate the transition from assessment to implementation in conservation planning, in order to help integrate assessment and implementation into a seamless process.

Extent of biodiversity surveys and ranges for endemic species in the Albertine Rift.

This article contains data on the estimated ranges of endemic species in the Albertine Rift both currently and under future climate change related to the research article entitled "Conservation of the endemic species of the Albertine Rift under future climate change" (Ayebare et al., 2018) [1]. Biodiversity surveys focused mainly on 5 taxa: birds, mammals, reptiles, amphibians and plants.

Simple avarone mimetics as selective agents against multidrug resistant cancer cells.

In this work, synthesis of alkylamino and aralkylamino derivatives of sesquiterpene quinone avarone and its model compound tert-butylquinone was described. For all obtained derivatives biological activity was studied. Cytotoxic activity of the synthesized derivatives towards multidrug resistant MDR human non-small cell lung carcinoma NCI-H460/R cells, their sensitive counterpart NCI-H460 and human normal keratinocytes (HaCaT) as well as detection of cell death superoxide anion generation were investigated.

Shortfalls in the global protected area network at representing marine biodiversity.

The first international goal for establishing marine protected areas (MPAs) to conserve the ocean's biodiversity was set in 2002. Since 2006, the Convention on Biological Diversity (CBD) has driven MPA establishment, with 193 parties committed to protecting >10% of marine environments globally by 2020, especially 'areas of particular importance for biodiversity' (Aichi target 11). This has resulted in nearly 10 million km(2) of new MPAs, a growth of ~360% in a decade.

Synthesis and biological activity of amino acid derivatives of avarone and its model compound.

A series of eighteen derivatives of marine sesquiterpene quinone avarone and its model system tert-butylquinone with amino acids has been synthesized by nucleophilic addition of amino acids to the quinones. In vitro cytotoxic activity toward human cancer cell lines (HeLa, A549, Fem-X, K562, MDA-MB-453) and normal MRC-5 cell line was determined. Several compounds showed very strong inhibitory activity with IC50 values less than 10 μM.

Global status of and prospects for protection of terrestrial geophysical diversity.

Conservation of representative facets of geophysical diversity may help conserve biological diversity as the climate changes. We conducted a global classification of terrestrial geophysical diversity and analyzed how land protection varies across geophysical diversity types. Geophysical diversity was classified in terms of soil type, elevation, and biogeographic realm and then compared to the global distribution of protected areas in 2012.

The performance and potential of protected areas.

Originally conceived to conserve iconic landscapes and wildlife, protected areas are now expected to achieve an increasingly diverse set of conservation, social and economic objectives. The amount of land and sea designated as formally protected has markedly increased over the past century, but there is still a major shortfall in political commitments to enhance the coverage and effectiveness of protected areas. Financial support for protected areas is dwarfed by the benefits that they provide, but these returns depend on effective management.

Targeting global protected area expansion for imperiled biodiversity.

Governments have agreed to expand the global protected area network from 13% to 17% of the world's land surface by 2020 (Aichi target 11) and to prevent the further loss of known threatened species (Aichi target 12). These targets are interdependent, as protected areas can stem biodiversity loss when strategically located and effectively managed. However, the global protected area estate is currently biased toward locations that are cheap to protect and away from important areas for biodiversity.

Dual effect of benzyl alcohol on α-glucosidase activity: efficient substrate for high yield transglucosylation and non-competitive inhibitor of its hydrolytic activity.

Benzyl alcohol, a potent anesthetic and bacteriostatic, can be efficiently glucosylated by α-glucosidase from Saccharomyces cerevisiae to produce benzyl alcohol α-glucoside with a 75% yield. However, while studying the transglucosylation reaction conditions, it was found out that benzyl alcohol is a non-competitive inhibitor of α-glucosidase's hydrolytic activity (Ki=18mM, toward maltose). Due to its interesting ability to be glycosylated by the enzyme and to inhibit its hydrolytic activity, we proposed a plausible mechanism for the phenolic α-glucosydase inhibitor's binding, since the mechanism of inhibition has not yet been elucidated.

How much does it cost to expand a protected area system? Some critical determining factors and ranges of costs for Queensland.

Many governments have recently gone on record promising large-scale expansions of protected areas to meet global commitments such as the Convention on Biological Diversity. As systems of protected areas are expanded to be more comprehensive, they are more likely to be implemented if planners have realistic budget estimates so that appropriate funding can be requested. Estimating financial budgets a priori must acknowledge the inherent uncertainties and assumptions associated with key parameters, so planners should recognize these uncertainties by estimating ranges of potential costs.

A new way to measure the world's protected area coverage.

Protected areas are effective at stopping biodiversity loss, but their placement is constrained by the needs of people. Consequently protected areas are often biased toward areas that are unattractive for other human uses. Current reporting metrics that emphasise the total area protected do not account for this bias.

The capacity of Australia's protected-area system to represent threatened species.

The acquisition or designation of new protected areas is usually based on criteria for representation of different ecosystems or land-cover classes, and it is unclear how well-threatened species are conserved within protected-area networks. Here, we assessed how Australia's terrestrial protected-area system (89 million ha, 11.6% of the continent) overlaps with the geographic distributions of threatened species and compared this overlap against a model that randomly placed protected areas across the continent and a spatially efficient model that placed protected areas across the continent to maximize threatened species' representation within the protected-area estate.

Electrochemical behavior and antioxidant and prooxidant activity of natural phenolics.

We have investigated the electrochemical oxidation of a number natural phenolics (salicylic acid, m-hydroxybenzoic acid, p-hydroxybenzoic acid, protocatechuic acid, o-coumaric acid, m-coumaric acid, p-coumaric acid, caffeic acid, quercetin and rutin) using cyclic voltammetry. The antioxidant properties of these compounds were also studied. A structural analysis of the tested phenolics suggests that multiple OH substitution and conjugation are important determinants of the free radical scavenging activity and electrochemical behavior.

When the Dog Bites.

In brief The physician treating an active brief Patient's dog bite injury faces some controversial treatment decisions: Should the wound be sutured? Is tetanus or rabies immunization indicated? Are prophylactic antibiotics appropriate?

Weight Lifting as a Cause of Bilateral Upper Extremity Compartment Syndrome.

In brief: Compartment syndrome caused by weight lifting occurs only rarely. In the case presented here, bilateral upper extremity compartment syndrome with rhabdomyolysis developed in a 30-year-old man who was an experienced weight lifter. Compartment pressure of 31 mm Hg in his right and left biceps, combined with other clinical findings, indicated that fasciotomy was necessary.

Hemoglobinuria after fraternity hazing.

We describe a 19-year-old male who presented with traumatic hemoglobinuria. We hypothesize that this patient has a genetic haptoglobin variant with a low hemoglobin binding capacity which resulted in hemoglobinuria after physical fraternity hazing. A review of the literature regarding traumatic hemoglobinuria supports the association between decreased baseline plasma haptoglobin levels and hemoglobinuria after trauma.