Publications by authors named "Seffir T Wendm"

Article Synopsis
  • Human rhinoviruses (RV) cause the common cold but can lead to severe health issues, especially in those with weakened immune systems.
  • Researchers sequenced over 1,000 RV genomes from both symptomatic and asymptomatic individuals during two distinct time frames in Washington State to study viral evolution.
  • The study found high genetic diversity, including the presence of various genotypes and recombination events, highlighting the need to explore the relationship between RV genetic variations and immune responses for better long-term strategies.
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SARS-CoV-2 transmission is largely driven by heterogeneous dynamics at a local scale, leaving local health departments to design interventions with limited information. We analyzed SARS-CoV-2 genomes sampled between February 2020 and March 2022 jointly with epidemiological and cell phone mobility data to investigate fine scale spatiotemporal SARS-CoV-2 transmission dynamics in King County, Washington, a diverse, metropolitan US county. We applied an approximate structured coalescent approach to model transmission within and between North King County and South King County alongside the rate of outside introductions into the county.

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SARS-CoV-2 transmission is largely driven by heterogeneous dynamics at a local scale, leaving local health departments to design interventions with limited information. We analyzed SARS-CoV-2 genomes sampled between February 2020 and March 2022 jointly with epidemiological and cell phone mobility data to investigate fine scale spatiotemporal SARS-CoV-2 transmission dynamics in King County, Washington, a diverse, metropolitan US county. We applied an approximate structured coalescent approach to model transmission within and between North King County and South King County alongside the rate of outside introductions into the county.

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