Publications by authors named "Seetha M Lakshmi Tamma"
Page 1 of 1
Synopsis of recent research by authors named "Seetha M Lakshmi Tamma"
Seetha M Lakshmi Tamma's research primarily focuses on the intracellular signaling mechanisms involved in T cell activation and cytokine synthesis, particularly in relation to the lectin jacalin and its effects when combined with CD28 costimulation.
Key findings reveal that jacalin plus CD28 stimulation significantly induces IL-4 secretion through the phosphorylation of signal transducer and activator of transcription (STAT)-6 and is influenced by the p38 MAPK pathway.
Additionally, Tamma's studies indicate that immunoglobulin D receptor cross-linking protects murine T cells from apoptosis, shedding light on potential therapeutic avenues for managing immune responses.
