Mitigation of arsenic poisoning induced oxidative stress and genotoxicity by Ocimum gratissimum L.

Arsenic toxicity is a major problem across the world due to geogenic activity and has been supposed to generate free radicals and genotoxicity among the arsenic-poisoned population. There is a need to find suitable free radical quenching compounds for the arsenic-induced free radical-affected population. In the present study, NaAsO- induced oxidative stress and genotoxicity were evaluated in Oryctolagus cuniculus L, and quenching competency of Ocimum species was examined by applying enzymatic and non-enzymatic in vitro tests, comet assay, and Random Amplified Polymorphic Deoxyribonucleic acid - Polymerase Chain Reaction (RAPD-PCR) methods.

Effect of acute exposure of sodium arsenite (Na3 Aso3) on some haematological parameters of Clarias batrachus (common Indian cat fish) in vivo.

The effect of acute arsenic exposure in the form of sodium arsenite (Na3Aso3) were studied on haematological parameters of Clarias batrachus. Three subleathal concentrations of sodium arsenite (5 ppm, 10 ppm, 15 ppm) were exposed to experimental set of 10 fishes in a glass aquarium filled with 40 L water. The parameters screened after 120 hrs exposure for each experimental set were Hb concentration, TEC, PCV and MCV MCH and MCHC were also calculated.