(Z)-N-(3-([1,1'-biphenyl]-2-yl)-4-heptyl-4-hydroxythiazolidin-2-ylidene)-4-bromobenzamide as carbonic anhydrase inhibitor: exploration of its in vitro and in silico studies.

Human Carbonic Anhydrase inhibitors (CAIs) have been clinically used to treat a variety of disorders, such as cancer, obesity, haemolytic anaemia, glaucoma, retinopathy, and epilepsy. To develop a Carbonic Anhydrase inhibitor, Iminothiazoline analogue ((Z)-N-(3-([1,1'-biphenyl]-2-yl)-4-heptyl-4-hydroxythiazolidin-2-ylidene)-4-bromobenzamide) was synthesized and characterized. Single crystal X-Ray diffraction studies and Hirshfeld surface analysis (HSA) were conducted to find the exact molecular structure as well as intermolecular interactions.

Visible-Light-Driven Carbon-Doped TiO-Based Nanocatalysts for Enhanced Activity toward Microbes and Removal of Dye.

Solar-driven photocatalytic approach is an attractive, clean, and effective way for decontamination of water. In this work, visible-light-activated TiO nanoflakes (TNFs) and carbon-doped TiO nanoflakes (C-TNFs) were synthesized via a facile hydrothermal route using different carbon sources. The as-synthesized nanostructures were successfully characterized by powder X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectroscopy, scanning electron microscopy (SEM), and transmission electron microscopy (TEM), critically disclosing the anatase nature containing titanium-oxygen having flake/platelet-like morphology with ∼32 nm in size, respectively.