Publications by authors named "Seema Pathan"

Objective: Urinary tract infections (UTIs) are common in neonates. Understanding the changes in the prevalence of common uropathogens is essential for early diagnosis and effective treatment of UTIs. This study aims to identify etiological agents and determine the local antibiotic susceptibility patterns of uropathogens causing UTIs.

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Coagulase-negative staphylococci (CoNS) are the most common isolates from blood culture in neonates resulting in high mortality and morbidity. This study investigated CoNS obtained from blood cultures of neonates for antibiotic resistance and virulence factors, and possible association with inflammatory response (C-reactive protein). A total of 93 CoNS isolates were collected from 76 blood cultures of neonates at the Maternity hospital in Kuwait in a six-month period and investigated for susceptibility to antibiotics, carriage of staphylococcal cassette chromosome mec (SCCmec), and virulence-associated genes.

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Article Synopsis
  • The study analyzed late-onset neonatal infections in a maternity hospital in Kuwait over five years, finding an incidence rate of 16.9 per 1000 live births.
  • Coagulase-negative Staphylococcus was the leading pathogen, while Klebsiella was the most frequent gram-negative bacteria, with significant antimicrobial resistance noted, especially among Klebsiella and Escherichia coli strains.
  • The research highlights a high incidence of infections similar to resource-poor settings and suggests that improving infection prevention measures could further decrease neonatal mortality rates.
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