Intaglio Surface Adaptation of Removable Partial Denture Framework Fabricated by Various Data Acquisition Techniques and Fabrication Approaches.

Objectives:  The aim of this study was to compare intaglio surface adaptation of the removable partial denture framework among various data acquisition techniques and fabrication approaches using three-dimensional comparison by metrology software.

Materials And Methods:  The partial edentulous typodont model with five digital superimposition landmarks was duplicated and scanned for the digital reference model. Three approaches were the conventional lost-wax (group I; LWT,  = 5), intraoral digital impressions combined with PolyJet printing and lost-wax (group II; IP-LWT,  = 5), and extraoral digital impressions combined with PolyJet printing and lost-wax (group III; EP-LWT,  = 5).

The Akt/mTOR pathway is activated in verrucous carcinoma of the oral cavity.

Background: The Akt/mTOR pathway is activated in many malignancies, including oral squamous cell carcinoma (OSCC). However, the role of the Akt/mTOR pathway in oral verrucous carcinoma (OVC), a low-grade variant of OSCC, remains unknown. Thus, the objective of this study was to investigate the activation level of important markers of the Akt/mTOR pathway in OVC and to compare the results with OSCC samples.