Publications by authors named "Sedighi M"

Carrageenan-based biomaterials have attracted considerable attention in recent years due to their unique biological properties, including their biodegradability, compatibility, and lack of adverse effects. These biomaterials exhibit a variety of beneficial properties, such as antiviral, antitumor, and immunomodulatory effects, which set them apart from other polysaccharides. Stimuli-responsive carrageenan-based biomaterials have attracted particular attention due to their unique properties, such as reducing systemic toxicity and controlling drug release.

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Research studies on Metal Organic Frameworks (MOF) based composites and their potential applications in environmental engineering and pollution control have recently emerged. An attractive material to form MOF composites is biochar (BC); a low-cost, highly porous carbonaceous by-product of biomass pyrolysis. This paper presents a critical review on MOF-biochar composites, focusing on fabrication, characterisation, modification, and applications in environmental protection and pollution control.

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  • The study investigates the installation of groundwater contamination remediation units in Bihar, India, focusing on contaminants like arsenic, iron, and fluoride, which are significant issues for drinking water quality in the region.
  • It reports that most arsenic remediation units are located near the River Ganges, while iron units are primarily in the eastern districts, and fluoride units are only south of the river, yet there's a mismatch between these installations and actual contamination levels.
  • The study suggests that outdated maps and administrative decisions may have influenced the placement of these units, leading to many areas still needing intervention while units are installed where they might not be as necessary.
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Objectives: This study investigated the effects of transcranial direct current stimulation (tDCS) before and during the mirror visual feedback (MVF) on hand grip strength (HGS) and range of motion of the affected hand in children with spastic hemiplegia cerebral palsy (SHCP).

Materials & Methods: Twelve children with SHCP participated in this randomized, crossover, and double-blind study. They were randomly exposed to one of four intervention conditions, including 1) a-tDCS-offline, 2) s-tDCS-offline, 3) a-tDCS-online, and 4) s-tDCS-online, with a one-week interval.

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Purpose: Evidence suggests that changes in the composition of gut microbiota may be linked to metabolic disorders including type 2 diabetes (T2D). The present study aims to evaluate the compositional changes of the intestinal microbiota in patients with T2D as compared to healthy individuals.

Methods: In this case-control study, there were 18 T2D patients and 18 healthy individuals who served as controls.

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In this research the possibility of using a photosynthetic microbial desalination cell (PhMDC) is investigated for desalination of power plant salty wastewater (PPSWW), along with power generation and organic load removal. The PhMDC was operated with anaerobic sludge in the anode chamber, microalgae in the cathode chamber, and different conductivities of PPSWW (10, 20, 40, and 55 mS cm) in the desalination chamber under different illumination modes (continuous light mode and light/dark mode). The highest power density (285.

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  • Dynamic hyperinflation in COPD leads to auto-PEEP, which increases the effort needed for breathing; Automatic tube compensation (ATC) aims to alleviate this.
  • In a study with 60 patients, results showed that activating ATC led to a significant decrease in auto-PEEP across all times of day, with greater reductions observed in stable COPD patients compared to those experiencing exacerbations.
  • Overall, while ATC activation benefits chronic COPD patients by reducing auto-PEEP, those with exacerbations showed less improvement.
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Background: Acid-base disturbances are frequently found in intensive care unit (ICU) patients. Base excess (BE) is commonly used to quantify the degree of metabolic impairment. We aimed to compare the predictive value of BE and Sequential Organ Failure Assessment (SOFA) score for mortality in ICU patients.

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  • * The study focused on a modified biochar with MgCl, determining the best conditions for optimal adsorption through various experiments, revealing key elements that enhance adsorption performance.
  • * Results showed the biochar's significant capacity for iron (289.45 mg/g) and phosphate (828.82 mg/g) removal, achieving high efficiencies (98.25% for iron and 96.22% for phosphate) under specific pH conditions, promoting a sustainable approach to utilizing hardwood waste.
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  • Acute coronary syndrome (ACS) is common in COVID-19 patients, potentially linked to high levels of interleukin-6 (IL-6) that contribute to heart injury.
  • *A study analyzed data from 1,753 hospitalized COVID-19 patients, finding ACS patients were older with more health issues, including diabetes and hypertension.
  • *Key indicators like IL-6, D-dimer, and troponin were significantly higher in ACS patients, suggesting these factors can help predict ACS risk in COVID-19 cases.
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  • Plasmid-mediated quinolone resistance (PMQR) in extended-spectrum β-lactamase (ESBL)-producing bacteria is linked to treatment failures and higher mortality, prompting a study in Babol, Iran, to assess the prevalence of PMQR genes.
  • From March 2022 to February 2023, 95 clinical isolates were analyzed, revealing that 71.57% were ESBL producers, with high frequencies of specific PMQR genes detected.
  • The study found a significant correlation between ESBL and PMQR genes, demonstrating the need for improved antimicrobial stewardship and surveillance to combat the spread of resistant bacteria.
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. Constipation is one of the most common gastrointestinal symptoms in children with neurological disorders. This study was performed to compare the therapeutic effect of polyethylene glycol (PEG) plus domperidone with PEG plus placebo in the treatment of chronic constipation in children with cerebral palsy.

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Background: Due to the increasing emergence of antibiotic resistance in Enterococcus faecalis (E. faecalis), it indicated as potentially opportunistic pathogen causing various healthcare-associated and life-threatening diseases around the world.

Objective: The aim of this meta-analysis was to evaluate the weighted pooled resistance rates in clinical E.

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Background: Balloon Pulmonary Valvuloplasty (BPV) is a procedure for Pulmonary Stenosis (PS) treatment. In this study, right ventricle (RV) performance was determined through 2D-Speckle Tracking Echocardiography (2D-STE).

Methods: The study involved 25 diagnosed children with PS undergoing BPV and 25 normal children.

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The relationship between gut microbiota and diabetes-related amino acids significantly impacts insulin resistance and obesity. We aimed to quantify two species and their correlation with branched-chain amino acids, aromatic amino acids, and glutamate in prediabetes (preDM) and type 2 diabetes mellitus (T2DM). Fecal samples were collected from 68 participants, including 21 with T2DM, 23 with preDM, and 24 with normal glycemic tolerance (NGT).

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Introduction: Spinal cord infarction (SCI) is a rare disease representing nearly 1% of all strokes with a wide variety of symptoms at presentation. SCI diagnosis is very challenging owing to its low incidence and the variety of symptoms, and could be misdiagnosed with neuromyelitis optica spectrum disorders (NMOSD).

Case Presentation: We describe the case of an 18-year-old girl who presented to the emergency department with acute neck pain and flaccid paralysis of the left upper and lower extremities.

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Wound healing is a complex process that orchestrates the coordinated action of various cells, cytokines and growth factors. Nanotechnology offers exciting new possibilities for enhancing the healing process by providing novel materials and approaches to deliver bioactive molecules to the wound site. This article elucidates recent advancements in utilizing nanoparticles, nanofibres and nanosheets for wound healing.

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The fig-milk dessert, a traditional and nutritionally rich treat infused with bioactive compounds, was subjected to a comprehensive analysis in this study. The novelty of this research lies in the investigation of the in vitro antioxidant, anticancer, and antimicrobial potential of the fig-milk dessert. This was accomplished through the utilization of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, Annexin/propidium iodide staining, microtiter plate-based assay and agar well diffusion, respectively, for the first time.

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This study examined the reliability of respirators using hierarchical analysis and multicriteria decision-making. The hierarchical structure, which consists of three assessment criteria and six product assemblies as decision possibilities, reveals that the priority of evaluation criteria follows the trend of cost, complexity and technology. Face-piece, triple-piece and visor assemblies have the highest failure rate, according to an analysis of product reliability at the assembly level.

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Unhealthy lifestyles have given rise to a growing epidemic of metabolic liver diseases, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). NAFLD often occurs as a consequence of obesity, and currently, there is no FDA-approved drug for its treatment. However, therapeutic oligonucleotides, such as RNA interference (RNAi), represent a promising class of pharmacotherapy that can target previously untreatable conditions.

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Dyslipidemia can increase the risk of heart attack and stroke due to the restriction of blood flow through the blood vessels. Dietary modification is an appropriate approach to reducing this phenomenon. This cross-sectional study aimed to evaluate major dietary patterns and the dietary inflammatory index (DII) in relation to dyslipidemia.

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Background: Valepotriate is an active ingredient of valerian () with strong antioxidant activity that is effective for numerous cardiovascular diseases.

Objective: The aim of this study was to investigate the effect of an active ingredient of extract on ischemia-reperfusion-induced cardiac injuries in male rats.

Methods: Thirty-two male rats were subjected to ischemia for 40 minutes and reperfusion for five days.

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Rhabdomyolysis is a potentially life-threatening condition induced by diverse mechanisms including drugs and toxins. We aimed to investigate the incidence of rhabdomyolysis occurrence in intoxicated patients with psychoactive substances. In this review, three databases (PubMed, Scopus, Web of Science) and search engine (Google Scholar) were searched by various keywords.

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Purpose: Mucopolysaccharidoses (MPS) are a group of rare genetic diseases and heart involvement is one of the important conflicts in most types, which may cause serious complications. We used M-Mode and two-dimensional speckle tracking echocardiography (2D-STE) to explore cardiovascular involvements in MPS patients.

Method: The present cross-sectional study investigated the frequency of cardiac involvements in MPS patients.

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