Ibn al-Haytham's ground theory of distance perception.

The 11th-century Arab scholar, Ibn al-Haytham, in his , offers a detailed, rigorous, empirically oriented explanation of distance perception that may be the first essentially modern, scientific theory of distance perception. Based on carefully described experiments, he argues that for distance to be perceived accurately: (1) the distance must lie along a continuous surface such as the ground; (2) the continuous surface must be visible; (3) the magnitudes of distances along the surface must be perceived and calibrated through bodily interaction (walking and reaching) with them; and finally (4) the distance must be moderate. Al-Haytham's work reached Europe early in the 13th century, and his was the dominant theory of distance perception there for about 400 years.

J. J. Gibson's "Ground Theory of Space Perception".

J. J. Gibson's ground theory of space perception is contrasted with Descartes' theory, which reduces all of space perception to the perception of distance and angular direction, relative to an abstract viewpoint.

Compression of perceived depth as a function of viewing conditions.

Purpose: The magnification produced by a low-vision telescope has been shown to compress perceived depth. Looking through such a telescope, however, also entails monocular viewing and visual field restriction, and these viewing conditions, taken together, were also shown to compress perceived depth. The research presented here quantitatively explores the separate effects of each of these viewing conditions on perceived depth.

Local and non-local effects on surface-mediated stereoscopic depth.

The magnitude and precision of stereoscopic depth between two probes is often determined by the disparity each has to a common background. If stereoscopic slant of the background is underestimated, a bias is introduced in the PSE of the probes (G. Mitchison & G.

Lab-on-a-chip technologies for proteomic analysis from isolated cells.

Lab-on-a-chip systems offer a versatile environment in which low numbers of cells and molecules can be manipulated, captured, detected and analysed. We describe here a microfluidic device that allows the isolation, electroporation and lysis of single cells. A431 human epithelial carcinoma cells, expressing a green fluorescent protein-labelled actin, were trapped by dielectrophoresis within an integrated lab-on-a-chip device containing saw-tooth microelectrodes.

Spatial compression produced by a stationary low-vision telescope.

Purpose: Geometrical analysis of the monocular information for visual space perception predicts that the magnification produced by a low-vision telescope will compress the depth dimension of space. To test this prediction we measured the compression in depth of perceived shape while looking through a stationary telescope. To control for the other aspects of telescopic viewing, apart from magnification, we also measured perception while looking through a plain tube having the same field of view.

Protein phase behavior and crystallization: effect of glycerol.

Glycerol is widely used as an additive to stabilize proteins in aqueous solution. We have studied the effect of up to 40 wt % glycerol on the crystallization of lysozyme from brine. As the glycerol concentration increased, progressively larger amounts of salt were needed to crystallize the protein.

Metabolic monitoring of the electrically stimulated single heart cell within a microfluidic platform.

A device based on five individually addressable microelectrodes, fully integrated within a microfluidic system, has been fabricated to enable the real-time measurement of ionic and metabolic fluxes from electrically active, beating single heart cells. The electrode array comprised one pair of pacing microelectrodes, used for field-stimulation of the cell, and three other microelectrodes, configured as an electrochemical lactate microbiosensor, that were used to measure the amounts of lactate produced by the heart cell. The device also allowed simultaneous in-situ microscopy, enabling optical measurements of cell contractility and fluorescence measurements of extracellular pH and cellular Ca2+.

Non-equilibrium behavior of sticky colloidal particles: beads, clusters and gels.

To understand the non-equilibrium behavior of colloidal particles with short-range attraction, we studied salt-induced aggregation of lysozyme. Optical microscopy revealed four regimes: bicontinuous texture, 'beads', large aggregates, and transient gelation. The interaction of a metastable liquid-liquid binodal and an ergodic to non-ergodic transition boundary inside the equilibrium crystallization region can explain our findings.

Equilibrium cluster formation in concentrated protein solutions and colloids.

Controlling interparticle interactions, aggregation and cluster formation is of central importance in a number of areas, ranging from cluster formation in various disease processes to protein crystallography and the production of photonic crystals. Recent developments in the description of the interaction of colloidal particles with short-range attractive potentials have led to interesting findings including metastable liquid-liquid phase separation and the formation of dynamically arrested states (such as the existence of attractive and repulsive glasses, and transient gels). The emerging glass paradigm has been successfully applied to complex soft-matter systems, such as colloid-polymer systems and concentrated protein solutions.

Spatial compression and adaptation with the low vision telescope.

Purpose: Geometrical analysis of monocular visual information specifying distance shows that a low vision telescope compresses optically specified distances by a factor about equal to its magnification. Using a group of eight visually healthy adults, we investigated the initial perceptual effect of putting on a 2x Galilean telescope and the adaptation produced by wearing the telescope.

Methods: Viewing was monocular, and the environment was only visible through the telescope.

Distance perception across spatial discontinuities.

We investigated the use of nested contact relations in perceiving the relative distance of locations on discontinuous surfaces. Observers viewed computer-generated displays under monocular static conditions and adjusted a marker to match the perceived distance of a cube. The marker and cube were raised above the ground by two different platforms separated by a gap.

Distance perception mediated through nested contact relations among surfaces.

In complex natural scenes, objects at different spatial locations can usually be related to each other through nested contact relations among adjoining surfaces. Our research asks how well human observers, under monocular static viewing conditions, are able to utilize this information in distance perception. We present computer-generated naturalistic scenes of a cube resting on a platform, which is in turn resting on the ground.

An investigation of the components used to calculate staff:student ratios in nursing and midwifery education.

This article describes the results of a census questionnaire sent to all colleges of nursing and midwifery and institutions of further and higher education undertaking English National Board for Nursing, Midwifery and Health Visiting (ENB) validated pre- and post-registration nursing and midwifery courses. The questionnaire was designed to identify the range of components, incorporated into formulae, used by the colleges and institutions to calculate staff:student ratios (SSRs), for each type of course. The results indicate that the majority of colleges and institutions use: [formula: see text] The definitions of staff and student within the formulae were either assumed or variously defined.

Body protein losses estimated by nitrogen balance and potassium-40 counting.

Body protein losses estimated from N balance were compared with those estimated by 40K counting. Six nonlactating dairy cows were fed an adequate N diet for 7 wk, a low N diet for 9 wk, and a replete N diet for 3 wk. The low N diet contained high cell wall grass hay plus ground corn, starch, and molasses.

Utilization of chopped and long alfalfa by dairy heifers.

Two physical forms of alfalfa hay, chopped and long, were fed at maintenance and for ad libitum consumption to dairy heifers to determine effects upon digestibility and energy utilization. Ad libitum intake was associated with lower digestibility of dry matter (56 versus 58%), neutral detergent fiber (45 versus 58%), and acid detergent fiber (45 versus 52%). Energy balance was 1.